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HC-056456

Name: HC-056456
Brand: TargetMol
SKU: T4604
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4604Cas No. 7733-96-2

Alias HC 056456, 3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide

HC-056456 (3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide) is a CatSper channel modulator.

HC-056456

🥰Excellent

Purity: 99.65%

Catalog No. T4604Alias HC 056456, 3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxideCas No. 7733-96-2

HC-056456 (3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide) is a CatSper channel modulator.

Pack Size	Price	Availability
1 mg	$30	In Stock
2 mg	$40	In Stock
5 mg	$64	In Stock
10 mg	$97	In Stock
25 mg	$178	In Stock
50 mg	$289	In Stock
100 mg	$478	In Stock
1 mL x 10 mM (in DMSO)	$70	In Stock

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Batch Information

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Purity:99.65%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	HC-056456 (3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide) is a CatSper channel modulator.
Targets&IC50	CatSper channel:3 µM
Synonyms	HC 056456, 3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide

Chemical Properties

Molecular Weight	306.32
Formula	C₁₂H₆N₂O₄S₂
Cas No.	7733-96-2
Smiles	[O-][n+]1onc(C(=O)c2cccs2)c1C(=O)c1cccs1
Relative Density.	1.67 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 150 mg/mL (489.68 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2646 mL	16.3228 mL	32.6456 mL	163.2280 mL
5 mM	0.6529 mL	3.2646 mL	6.5291 mL	32.6456 mL
10 mM	0.3265 mL	1.6323 mL	3.2646 mL	16.3228 mL
20 mM	0.1632 mL	0.8161 mL	1.6323 mL	8.1614 mL
50 mM	0.0653 mL	0.3265 mL	0.6529 mL	3.2646 mL
100 mM	0.0326 mL	0.1632 mL	0.3265 mL	1.6323 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc