Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Elomotecan (BN 80927 free base), a camptothecin analog from the homocamptothecin family (hCPT), serves as a potent inhibitor of topoisomerases I and II. It effectively reduces the proliferation of various tumor cells more significantly than other reference anticancer drugs targeting the same topoisomerases [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 2,720.00 | |
50 mg | 10-14 weeks | $ 3,580.00 | |
100 mg | 10-14 weeks | $ 4,900.00 |
Description | Elomotecan (BN 80927 free base), a camptothecin analog from the homocamptothecin family (hCPT), serves as a potent inhibitor of topoisomerases I and II. It effectively reduces the proliferation of various tumor cells more significantly than other reference anticancer drugs targeting the same topoisomerases [1]. |
In vitro | WEHI-539 induces noticeable PARP cleavage in Ovcar-4 (5 μM in Ovcar-4.) and Ovsaho (1 μM in Ovsaho) cells. WEHI-539 augments Carboplatin induced caspase 3/7 activity, PARP cleavage, and annexin V labeling.[2] |
Synonyms | BN 80927 free base |
Molecular Weight | 522.04 |
Formula | C29H32ClN3O4 |
CAS No. | 220998-10-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Elomotecan 220998-10-7 BN80927 BN 80927 free base BN-80927 BN 80927 inhibitor inhibit