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BAY-184

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Catalog No. T203636Cas No. 2520347-03-7
Alias BAY184

BAY-184 is a selective oral inhibitor of KAT6A and KAT6B with IC50 values of 71 nM and 83 nM, respectively. This compound suppresses estrogen receptor α (ERα) transcriptional activity and impedes cell proliferation across various breast cancer subtypes as well as tumor growth.

BAY-184

BAY-184

😃Good
Purity: 98.87%
Catalog No. T203636Alias BAY184Cas No. 2520347-03-7
BAY-184 is a selective oral inhibitor of KAT6A and KAT6B with IC50 values of 71 nM and 83 nM, respectively. This compound suppresses estrogen receptor α (ERα) transcriptional activity and impedes cell proliferation across various breast cancer subtypes as well as tumor growth.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$38-In Stock
5 mg$60-In Stock
10 mg$98-In Stock
25 mg$197-In Stock
50 mg$318-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:98.87%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
BAY-184 is a selective oral inhibitor of KAT6A and KAT6B with IC50 values of 71 nM and 83 nM, respectively. This compound suppresses estrogen receptor α (ERα) transcriptional activity and impedes cell proliferation across various breast cancer subtypes as well as tumor growth.
SynonymsBAY184
Chemical Properties
Molecular Weight420.48
FormulaC23H20N2O4S
Cas No.2520347-03-7
SmilesO=C(NS(=O)(=O)C=1C=CC=CC1C=2C=CC=CC2)C=3OC=4C=C(C=CC4C3)N(C)C
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 95 mg/mL (225.93 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3782 mL11.8912 mL23.7823 mL118.9117 mL
5 mM0.4756 mL2.3782 mL4.7565 mL23.7823 mL
10 mM0.2378 mL1.1891 mL2.3782 mL11.8912 mL
20 mM0.1189 mL0.5946 mL1.1891 mL5.9456 mL
50 mM0.0476 mL0.2378 mL0.4756 mL2.3782 mL
100 mM0.0238 mL0.1189 mL0.2378 mL1.1891 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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