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BAY-184

🥰Excellent
Catalog No. T203636Cas No. 2520347-03-7
Alias BAY184

BAY-184 is a selective oral inhibitor of KAT6A and KAT6B with IC50 values of 71 nM and 83 nM, respectively. This compound suppresses estrogen receptor α (ERα) transcriptional activity and impedes cell proliferation across various breast cancer subtypes as well as tumor growth.

BAY-184

BAY-184

🥰Excellent
Purity: 98.87%
Catalog No. T203636Alias BAY184Cas No. 2520347-03-7
BAY-184 is a selective oral inhibitor of KAT6A and KAT6B with IC50 values of 71 nM and 83 nM, respectively. This compound suppresses estrogen receptor α (ERα) transcriptional activity and impedes cell proliferation across various breast cancer subtypes as well as tumor growth.
Pack SizePriceAvailabilityQuantity
2 mg$38In Stock
5 mg$60In Stock
10 mg$98In Stock
25 mg$197In Stock
50 mg$318In Stock
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Purity:98.87%
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Product Introduction

Bioactivity
Description
BAY-184 is a selective oral inhibitor of KAT6A and KAT6B with IC50 values of 71 nM and 83 nM, respectively. This compound suppresses estrogen receptor α (ERα) transcriptional activity and impedes cell proliferation across various breast cancer subtypes as well as tumor growth.
SynonymsBAY184
Chemical Properties
Molecular Weight420.48
FormulaC23H20N2O4S
Cas No.2520347-03-7
SmilesO=C(NS(=O)(=O)C=1C=CC=CC1C=2C=CC=CC2)C=3OC=4C=C(C=CC4C3)N(C)C
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 95 mg/mL (225.93 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3782 mL11.8912 mL23.7823 mL118.9117 mL
5 mM0.4756 mL2.3782 mL4.7565 mL23.7823 mL
10 mM0.2378 mL1.1891 mL2.3782 mL11.8912 mL
20 mM0.1189 mL0.5946 mL1.1891 mL5.9456 mL
50 mM0.0476 mL0.2378 mL0.4756 mL2.3782 mL
100 mM0.0238 mL0.1189 mL0.2378 mL1.1891 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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