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HTMT dimaleate

Name: HTMT dimaleate
Brand: TargetMol
SKU: T22842
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22842Cas No. 195867-54-0

Alias Histamine Trifluoromethyl Toluidide Dimaleate

HTMT dimaleate (Histamine Trifluoromethyl Toluidide Dimaleate) is an H1 and H2 receptor agonist.

HTMT dimaleate

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Purity: 99.51%

Catalog No. T22842Alias Histamine Trifluoromethyl Toluidide DimaleateCas No. 195867-54-0

HTMT dimaleate (Histamine Trifluoromethyl Toluidide Dimaleate) is an H1 and H2 receptor agonist.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$30	In Stock	In Stock
5 mg	$89	In Stock	In Stock
10 mg	$135	In Stock	In Stock
25 mg	$228	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.51%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

HTMT dimaleate AI Summary

HTMT dimaleate exhibits a range of bioactivities, including antifungal and antibacterial properties. It demonstrates antifungal activity against Candida albicans with an inhibition rate of 2.76%, although it shows slight negative activity against Cryptococcus neoformans with an inhibition of -4.87%. In terms of antibacterial activity, HTMT dimaleate inhibits Escherichia coli by 3.85%, Klebsiella pneumoniae by 6.44%, Pseudomonas aeruginosa notably by 23.47%, Acinetobacter baumannii by 8.6%, and Staphylococcus aureus MRSA by 7.23%..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	HTMT dimaleate (Histamine Trifluoromethyl Toluidide Dimaleate) is an H1 and H2 receptor agonist.
Synonyms	Histamine Trifluoromethyl Toluidide Dimaleate

Chemical Properties

Molecular Weight	614.57
Formula	C₂₇H₃₃F₃N₄O₉
Cas No.	195867-54-0
Smiles	[H]OC(/C=C\C(O[H])=O)=O.[H]OC(/C=C\C(O[H])=O)=O.CC(NCCC1=CNC=N1)CCCCC(NC2=CC=C(C(F)(F)F)C=C2)=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: < 60 mg/mL, Sonication is recommended.

DMSO: 150 mg/mL (244.07 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6272 mL	8.1358 mL	16.2715 mL	81.3577 mL
5 mM	0.3254 mL	1.6272 mL	3.2543 mL	16.2715 mL
10 mM	0.1627 mL	0.8136 mL	1.6272 mL	8.1358 mL
20 mM	0.0814 mL	0.4068 mL	0.8136 mL	4.0679 mL
50 mM	0.0325 mL	0.1627 mL	0.3254 mL	1.6272 mL
100 mM	0.0163 mL	0.0814 mL	0.1627 mL	0.8136 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc