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Boc-NH-C6-Br

Name: Boc-NH-C6-Br
Brand: TargetMol
SKU: T17654
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T17654Cas No. 142356-33-0

Boc-NH-C6-Br is a cleavable linker used in antibody-drug conjugates (ADC).

Boc-NH-C6-Br

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Purity: 95.09%

Catalog No. T17654Cas No. 142356-33-0

Boc-NH-C6-Br is a cleavable linker used in antibody-drug conjugates (ADC).

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
200 mg	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:95.09%

Appearance:Liquid

Color:Transparent

Resource Download

COA GC HNMR

Product Introduction

Bioactivity

Description

Boc-NH-C6-Br is a cleavable linker used in antibody-drug conjugates (ADC).

Chemical Properties

Molecular Weight	280.2
Formula	C₁₁H₂₂BrNO₂
Cas No.	142356-33-0
Smiles	C(NCCCCCCBr)(OC(C)(C)C)=O
Relative Density.	1.192 g/cm3 at 20℃ (lit.)

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40 mg/mL (142.76 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5689 mL	17.8444 mL	35.6888 mL	178.4440 mL
5 mM	0.7138 mL	3.5689 mL	7.1378 mL	35.6888 mL
10 mM	0.3569 mL	1.7844 mL	3.5689 mL	17.8444 mL
20 mM	0.1784 mL	0.8922 mL	1.7844 mL	8.9222 mL
50 mM	0.0714 mL	0.3569 mL	0.7138 mL	3.5689 mL
100 mM	0.0357 mL	0.1784 mL	0.3569 mL	1.7844 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc