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Boc-NH-C6-Br

Name: Boc-NH-C6-Br
Brand: TargetMol
SKU: T17654
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T17654Cas No. 142356-33-0

Boc-NH-C6-Br is a cleavable linker used in antibody-drug conjugates (ADC).

Boc-NH-C6-Br

🥰Excellent

Purity: 95.09%

Catalog No. T17654Cas No. 142356-33-0

Boc-NH-C6-Br is a cleavable linker used in antibody-drug conjugates (ADC).

Pack Size	Price	Availability	Quantity
200 mg	$29	In Stock

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Batch Information

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Purity:95.09%

Resource Download

COA GC HNMR

Product Introduction

Bioactivity

Description

Boc-NH-C6-Br is a cleavable linker used in antibody-drug conjugates (ADC).

Chemical Properties

Molecular Weight	280.2
Formula	C₁₁H₂₂BrNO₂
Cas No.	142356-33-0
Smiles	C(NCCCCCCBr)(OC(C)(C)C)=O
Relative Density.	1.192 g/cm3 at 20℃ (lit.)
Color	Transparent
Appearance	Liquid

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40 mg/mL (142.76 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5689 mL	17.8444 mL	35.6888 mL	178.4440 mL
5 mM	0.7138 mL	3.5689 mL	7.1378 mL	35.6888 mL
10 mM	0.3569 mL	1.7844 mL	3.5689 mL	17.8444 mL
20 mM	0.1784 mL	0.8922 mL	1.7844 mL	8.9222 mL
50 mM	0.0714 mL	0.3569 mL	0.7138 mL	3.5689 mL
100 mM	0.0357 mL	0.1784 mL	0.3569 mL	1.7844 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc