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CDK9-IN-10

Name: CDK9-IN-10
Brand: TargetMol
SKU: T10742
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T10742Cas No. 3542-63-0

CDK9-IN-10 is a potent inhibitor of CDK9 and serves as the ligand for the PROTAC CDK9 degrader-2.

CDK9-IN-10

🥰Excellent

Purity: 99.8%

Catalog No. T10742Cas No. 3542-63-0

CDK9-IN-10 is a potent inhibitor of CDK9 and serves as the ligand for the PROTAC CDK9 degrader-2.

Pack Size	Price	Availability
2 mg	$30	In Stock
5 mg	$45	In Stock
10 mg	$79	In Stock
25 mg	$156	In Stock
50 mg	$247	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.8%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description

CDK9-IN-10 is a potent inhibitor of CDK9 and serves as the ligand for the PROTAC CDK9 degrader-2.

Chemical Properties

Molecular Weight	360.36
Formula	C₂₂H₁₆O₅
Cas No.	3542-63-0
Smiles	Oc1cc(OCc2ccccc2)c(O)c2oc(cc(=O)c12)-c1ccccc1
Relative Density.	1.381 g/cm3 (Predicted)
Color	Orange
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (249.75 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7750 mL	13.8750 mL	27.7500 mL	138.7501 mL
5 mM	0.5550 mL	2.7750 mL	5.5500 mL	27.7500 mL
10 mM	0.2775 mL	1.3875 mL	2.7750 mL	13.8750 mL
20 mM	0.1388 mL	0.6938 mL	1.3875 mL	6.9375 mL
50 mM	0.0555 mL	0.2775 mL	0.5550 mL	2.7750 mL
100 mM	0.0278 mL	0.1388 mL	0.2775 mL	1.3875 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc