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UCB9608

Name: UCB9608
Brand: TargetMol
SKU: TQ0009
Price: 50 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TQ0009Cas No. 1616413-96-7

UCB9608 is a selective and orally active PI4KIIIβ inhibitor (IC50: 11 nM), selective over PI3KC2 α, β, and γ lipid kinases.

UCB9608

🥰Excellent

Purity: 99.59%

Catalog No. TQ0009Cas No. 1616413-96-7

UCB9608 is a selective and orally active PI4KIIIβ inhibitor (IC50: 11 nM), selective over PI3KC2 α, β, and γ lipid kinases.

Pack Size	Price	Availability
1 mg	$50	In Stock
5 mg	$119	In Stock
10 mg	$173	In Stock
25 mg	$291	In Stock
50 mg	$416	In Stock
100 mg	$592	In Stock
200 mg	$798	In Stock
1 mL x 10 mM (in DMSO)	$130	In Stock

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Batch Information

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Purity:99.59%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	UCB9608 is a selective and orally active PI4KIIIβ inhibitor (IC50: 11 nM), selective over PI3KC2 α, β, and γ lipid kinases.
Targets&IC50	PI4KIIIβ:11 nM (cell free)

Chemical Properties

Molecular Weight	410.47
Formula	C₂₀H₂₆N₈O₂
Cas No.	1616413-96-7
Smiles	COc1ccc(NC(=O)N2CCN([C@@H](C)C2)c2nc(N)nc3n(C)ncc23)c(C)c1
Relative Density.	1.42 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 70 mg/mL (170.54 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4362 mL	12.1812 mL	24.3623 mL	121.8116 mL
5 mM	0.4872 mL	2.4362 mL	4.8725 mL	24.3623 mL
10 mM	0.2436 mL	1.2181 mL	2.4362 mL	12.1812 mL
20 mM	0.1218 mL	0.6091 mL	1.2181 mL	6.0906 mL
50 mM	0.0487 mL	0.2436 mL	0.4872 mL	2.4362 mL
100 mM	0.0244 mL	0.1218 mL	0.2436 mL	1.2181 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc