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Dolasetron

🥰Excellent
Catalog No. T4568Cas No. 115956-12-2
Alias MDL-73147

Dolasetron (MDL-73147)(MDL-73147) is a serotonin 5-HT3 receptor antagonist. Dolasetron is used to treat nausea and vomiting following chemotherapy.

Dolasetron
Other Forms of Dolasetron:
Dolasetron MesylateT22313115956-13-3
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Dolasetron

🥰Excellent
Purity: 99.86%
Catalog No. T4568Alias MDL-73147Cas No. 115956-12-2
Dolasetron (MDL-73147)(MDL-73147) is a serotonin 5-HT3 receptor antagonist. Dolasetron is used to treat nausea and vomiting following chemotherapy.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$40In StockIn Stock
10 mg$60In StockIn Stock
25 mg$123In StockIn Stock
50 mg$198In StockIn Stock
100 mg$297In StockIn Stock
500 mg$733In StockIn Stock
1 mL x 10 mM (in DMSO)$44In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.86%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
Dolasetron (MDL-73147)(MDL-73147) is a serotonin 5-HT3 receptor antagonist. Dolasetron is used to treat nausea and vomiting following chemotherapy.
SynonymsMDL-73147
Chemical Properties
Molecular Weight324.37
FormulaC19H20N2O3
Cas No.115956-12-2
SmilesO=C(O[C@@H]1C[C@H]2C[C@@H]3C[C@@H](C1)N2CC3=O)c1c[nH]c2ccccc12
Relative Density.1.37 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (154.14 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0829 mL15.4145 mL30.8290 mL154.1450 mL
5 mM0.6166 mL3.0829 mL6.1658 mL30.8290 mL
10 mM0.3083 mL1.5414 mL3.0829 mL15.4145 mL
20 mM0.1541 mL0.7707 mL1.5414 mL7.7072 mL
50 mM0.0617 mL0.3083 mL0.6166 mL3.0829 mL
100 mM0.0308 mL0.1541 mL0.3083 mL1.5414 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

Serotonin ReceptorMDL73147MDL 73147InhibitorinhibitDolasetron5-hydroxytryptamine Receptor5HTReceptor5-HT35-HT Receptor5HT Receptor
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