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Fenamic acid

Name: Fenamic acid
Brand: TargetMol
SKU: T22330
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22330Cas No. 91-40-7

Alias N-Phenylanthranilic acid, Diphenylamine-2-carboxylic acid, 2-Anilinobenzoic acid, 2-(Phenylamino)benzoic acid

Fenamic acid (N-Phenylanthranilic acid) is a chloride channel blocker that causes renal papillary necrosis in rats. Fenamic acid serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), including flufenamic acid, tolfenamic acid, mefenamic acid, and meclofenamic acid.

Fenamic acid

🥰Excellent

Purity: 99.6%

Catalog No. T22330Alias N-Phenylanthranilic acid, Diphenylamine-2-carboxylic acid, 2-Anilinobenzoic acid, 2-(Phenylamino)benzoic acidCas No. 91-40-7

Pack Size	Price	USA Warehouse	Global Warehouse
100 mg	$33	In Stock	In Stock
200 mg	$48	In Stock	In Stock
500 mg	$78	In Stock	In Stock
1 g	$116	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.6%

Appearance:solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Fenamic acid (N-Phenylanthranilic acid) is a chloride channel blocker that causes renal papillary necrosis in rats. Fenamic acid serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), including flufenamic acid, tolfenamic acid, mefenamic acid, and meclofenamic acid.
Synonyms	N-Phenylanthranilic acid, Diphenylamine-2-carboxylic acid, 2-Anilinobenzoic acid, 2-(Phenylamino)benzoic acid

Chemical Properties

Molecular Weight	213.2319
Formula	C₁₃H₁₁NO₂
Cas No.	91-40-7
Smiles	OC(=O)C1=C(NC2=CC=CC=C2)C=CC=C1
Relative Density.	1.1544 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (257.94 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (18.76 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.6897 mL	23.4486 mL	46.8973 mL	234.4865 mL
5 mM	0.9379 mL	4.6897 mL	9.3795 mL	46.8973 mL
10 mM	0.4690 mL	2.3449 mL	4.6897 mL	23.4486 mL
20 mM	0.2345 mL	1.1724 mL	2.3449 mL	11.7243 mL
50 mM	0.0938 mL	0.4690 mL	0.9379 mL	4.6897 mL
100 mM	0.0469 mL	0.2345 mL	0.4690 mL	2.3449 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc