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5,6-Dimethyl-1H-benzo[d]imidazole

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Catalog No. T4824Cas No. 582-60-5
Alias 5,6-Dimethylbenzimidazole

5,6-Dimethyl-1H-benzo[d]imidazole (5,6-Dimethylbenzimidazole) is an intermediate in Riboflavin metabolism and is the penultimate step in the synthesis of alpha-Ribazole. It is converted from Riboflavin and subsequently transformed into N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole by the enzyme nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21).

5,6-Dimethyl-1H-benzo[d]imidazole

5,6-Dimethyl-1H-benzo[d]imidazole

🥰Excellent
Purity: 99.39%
Catalog No. T4824Alias 5,6-DimethylbenzimidazoleCas No. 582-60-5
5,6-Dimethyl-1H-benzo[d]imidazole (5,6-Dimethylbenzimidazole) is an intermediate in Riboflavin metabolism and is the penultimate step in the synthesis of alpha-Ribazole. It is converted from Riboflavin and subsequently transformed into N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole by the enzyme nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 g$29-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.39%
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Product Introduction

Bioactivity
Description
5,6-Dimethyl-1H-benzo[d]imidazole (5,6-Dimethylbenzimidazole) is an intermediate in Riboflavin metabolism and is the penultimate step in the synthesis of alpha-Ribazole. It is converted from Riboflavin and subsequently transformed into N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole by the enzyme nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21).
Synonyms5,6-Dimethylbenzimidazole
Chemical Properties
Molecular Weight146.19
FormulaC9H10N2
Cas No.582-60-5
SmilesCc1cc2nc[nH]c2cc1C
Relative Density.1.145 g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (307.82 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (13.68 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM6.8404 mL34.2021 mL68.4041 mL342.0207 mL
5 mM1.3681 mL6.8404 mL13.6808 mL68.4041 mL
10 mM0.6840 mL3.4202 mL6.8404 mL34.2021 mL
20 mM0.3420 mL1.7101 mL3.4202 mL17.1010 mL
50 mM0.1368 mL0.6840 mL1.3681 mL6.8404 mL
100 mM0.0684 mL0.3420 mL0.6840 mL3.4202 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Keywords

InhibitorinhibitEndogenousMetaboliteEndogenous Metabolite5,6-Dimethyl-1H-benzo[d]imidazole5,6Dimethyl1Hbenzo[d]imidazole5,6 Dimethyl 1H benzo[d]imidazole
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