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Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $30 | In Stock | |
| 100 mg | $40 | In Stock | |
| 500 mg | $73 | In Stock | |
| 1 g | $98 | In Stock | |
| 5 g | $155 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $39 | In Stock |
| Description | Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB. |
| In vitro | Diethylmaleate and iodoacetate in combination caused augmented damage to astrocytes in a time- and concentration-dependent manner[1]. |
| In vivo | In TR- rats, in spite of a dilatation of the Golgi apparatus and of the endoplasmic reticulum. It is unlikely that the alterations in the Golgi apparatus (and the endoplasmic reticulum) induced by diethylmaleate play a role in the canalicular secretion of diethylmaleate. |
| Synonyms | Maleic acid, diethyl ester, DIETHYL MALEATE |
| Molecular Weight | 172.18 |
| Formula | C8H12O4 |
| Cas No. | 141-05-9 |
| Smiles | C(/C=C\C(OCC)=O)(OCC)=O |
| Relative Density. | 1.066. Temperature:20 °C. |
| Color | Transparent |
| Appearance | Liquid |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/mL (348.47 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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