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Citicoline sodium

🥰Excellent
Catalog No. T1208Cas No. 33818-15-4
Alias Citicoline sodium salt, CDP-choline

Citicoline sodium (CDP-choline) is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicoline sodium demonstrates protective effects in cerebral ischemia, traumatic brain injury, and memory disorders. Exogenous administration of citicoline to rodents (500 mg/kg i.p. immediately after ischemia and at 3-h reperfusion) has been shown to stimulate the synthesis of phosphatidylcholine, sphingomyelin, and cardiolipin and to attenuate the release of arachidonic acid and the accumulation of ceramide.

Citicoline sodium
Other Forms of Citicoline sodium:
CiticolineT0136987-78-0
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Citicoline sodium

🥰Excellent
Purity: 99.37%
Catalog No. T1208Alias Citicoline sodium salt, CDP-cholineCas No. 33818-15-4
Citicoline sodium (CDP-choline) is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicoline sodium demonstrates protective effects in cerebral ischemia, traumatic brain injury, and memory disorders. Exogenous administration of citicoline to rodents (500 mg/kg i.p. immediately after ischemia and at 3-h reperfusion) has been shown to stimulate the synthesis of phosphatidylcholine, sphingomyelin, and cardiolipin and to attenuate the release of arachidonic acid and the accumulation of ceramide.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mg$30In StockIn Stock
100 mg$42In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.37%
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Product Introduction

Bioactivity
Description
Citicoline sodium (CDP-choline) is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicoline sodium demonstrates protective effects in cerebral ischemia, traumatic brain injury, and memory disorders. Exogenous administration of citicoline to rodents (500 mg/kg i.p. immediately after ischemia and at 3-h reperfusion) has been shown to stimulate the synthesis of phosphatidylcholine, sphingomyelin, and cardiolipin and to attenuate the release of arachidonic acid and the accumulation of ceramide.
SynonymsCiticoline sodium salt, CDP-choline
Chemical Properties
Molecular Weight510.31
FormulaC14H25N4NaO11P2
Cas No.33818-15-4
Smiles[C@@H]1(n2c(=O)nc(cc2)N)O[C@@H]([C@H]([C@H]1O)O)COP(=O)(OP(=O)(OCC[N+](C)(C)C)[O-])[O-].[Na+]
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 200 mg/mL (391.92 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.9596 mL9.7980 mL19.5959 mL97.9797 mL
5 mM0.3919 mL1.9596 mL3.9192 mL19.5959 mL
10 mM0.1960 mL0.9798 mL1.9596 mL9.7980 mL
20 mM0.0980 mL0.4899 mL0.9798 mL4.8990 mL
50 mM0.0392 mL0.1960 mL0.3919 mL1.9596 mL
100 mM0.0196 mL0.0980 mL0.1960 mL0.9798 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

phosphatidylcholineInhibitorinhibitEndogenousMetaboliteEndogenous MetaboliteCytidine diphosphate-cholineCytidine 5'-diphosphocholineCiticoline sodiumCiticolineApoptosis
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