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O4I2

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Catalog No. T2437Cas No. 165682-93-9
Alias O-4I2, O4I2

O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts.

O4I2

O4I2

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Purity: 99.84%
Catalog No. T2437Alias O-4I2, O4I2Cas No. 165682-93-9
O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$30In StockIn Stock
10 mg$38In StockIn Stock
25 mg$71In StockIn Stock
50 mg$119In StockIn Stock
100 mg$221In StockIn Stock
200 mg$329-In Stock
1 mL x 10 mM (in DMSO)$31In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.84%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts.
In vitro
O4I2 activates Oct3/4 expression in HEK293 and embryonal NCCIT cells, and also in Oct-deficient HeLa and terminally differentiated human fibroblasts, and also induces other pluripotency-associated genes such as Lin28 and Nanog. [1]
SynonymsO-4I2, O4I2
Chemical Properties
Molecular Weight282.75
FormulaC12H11ClN2O2S
Cas No.165682-93-9
SmilesCCOC(=O)C1=CSC(NC2=CC=C(Cl)C=C2)=N1
Relative Density.1.382 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 14.1 mg/mL (49.87 mM), Sonication is recommended.
DMSO: 28.3 mg/mL (100.09 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM3.5367 mL17.6835 mL35.3669 mL176.8347 mL
5 mM0.7073 mL3.5367 mL7.0734 mL35.3669 mL
10 mM0.3537 mL1.7683 mL3.5367 mL17.6835 mL
20 mM0.1768 mL0.8842 mL1.7683 mL8.8417 mL
DMSO
1mg5mg10mg50mg
50 mM0.0707 mL0.3537 mL0.7073 mL3.5367 mL
100 mM0.0354 mL0.1768 mL0.3537 mL1.7683 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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