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O4I2

Name: O4I2
Brand: TargetMol
SKU: T2437
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2437Cas No. 165682-93-9

Alias O-4I2, O4I2

O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts.

O4I2

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Purity: 99.84%

Catalog No. T2437Alias O-4I2, O4I2Cas No. 165682-93-9

O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts.

Pack Size	Price	Availability
5 mg	$30	In Stock
10 mg	$38	In Stock
25 mg	$71	In Stock
50 mg	$119	In Stock
100 mg	$221	In Stock
200 mg	$329	In Stock
1 mL x 10 mM (in DMSO)	$31	In Stock

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Purity:99.84%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts.
In vitro	O4I2 activates Oct3/4 expression in HEK293 and embryonal NCCIT cells, and also in Oct-deficient HeLa and terminally differentiated human fibroblasts, and also induces other pluripotency-associated genes such as Lin28 and Nanog. [1]
Synonyms	O-4I2, O4I2

Chemical Properties

Molecular Weight	282.75
Formula	C₁₂H₁₁ClN₂O₂S
Cas No.	165682-93-9
Smiles	CCOC(=O)C1=CSC(NC2=CC=C(Cl)C=C2)=N1
Relative Density.	1.382 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 14.1 mg/mL (49.87 mM), Sonication is recommended.

DMSO: 28.3 mg/mL (100.09 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5367 mL	17.6835 mL	35.3669 mL	176.8347 mL
5 mM	0.7073 mL	3.5367 mL	7.0734 mL	35.3669 mL
10 mM	0.3537 mL	1.7683 mL	3.5367 mL	17.6835 mL
20 mM	0.1768 mL	0.8842 mL	1.7683 mL	8.8417 mL

DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0707 mL	0.3537 mL	0.7073 mL	3.5367 mL
100 mM	0.0354 mL	0.1768 mL	0.3537 mL	1.7683 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc