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Anti-Elafin Antibody (7F242)
😃Good
Catalog No. TMAY-02271
Alias WFDC14, WAP3, SKALP, peptidase inhibitor 3, MGC13613, ESI, cementoin
Anti-Elafin Antibody (7F242) is a Rabbit antibody targeting Elafin. Anti-Elafin Antibody (7F242) can be used in ELISA.
Anti-Elafin Antibody (7F242)
Anti-Elafin Antibody (7F242)
😃Good
Catalog No. TMAY-02271Alias WFDC14, WAP3, SKALP, peptidase inhibitor 3, MGC13613, ESI, cementoin
Anti-Elafin Antibody (7F242) is a Rabbit antibody targeting Elafin. Anti-Elafin Antibody (7F242) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $270 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Elafin Antibody (7F242) is a Rabbit antibody targeting Elafin. Anti-Elafin Antibody (7F242) can be used in ELISA. |
| Alias | WFDC14, WAP3, SKALP, peptidase inhibitor 3, MGC13613, ESI, cementoin |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 7F242 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human PI3 / Elafin / WFDC14 (rh PI3 / Elafin / WFDC14; TMPY-01909; NP_002629.1; Met1-Gln117). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Elafin, also known as Elastase-specific inhibitor, Peptidase inhibitor 3, Protease inhibitor WAP3, Skin-derived antileukoproteinase, WAP four-disulfide core domain protein 14, PI3, WAP3 and WFDC14, is a secreted protein that contains one WAP domain. Elafin / PI3 consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain at the N-terminus serves as an anchor to localize elafin covalently to specific sites on extracellular matrix proteins. The serine anti-protease Elafin / PI3 is expressed by monocytes, alveolar macrophages, neutrophils, and at mucosal surfaces and possesses antimicrobial activity. It is also known to reduce lipopolysaccharide-induced neutrophil influx into murine alveoli as well as to abrogate lipopolysaccharide-induced production of matrix metalloprotease 9, macrophage inhibitory protein 2, and tumor necrosis factor-alpha by as-yet unidentified mechanisms. Elafin / PI3 is a neutrophil serine protease inhibitor expressed in lung and displaying anti-inflammatory and anti-bacterial properties. Elafin / PI3 is a neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis. Elafin / PI3 will regulate proteolytic enzymes during menstruation and will contribute to the innate defense against uterine infection. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human PI3 / Elafin / WFDC14 protein (TMPY-01909) |
| Antigen Species | Human |
| Biology Area | Serine Proteases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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