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Anti-Elafin Antibody (7F242) (Synonyms: WFDC14, WAP3, SKALP, peptidase inhibitor 3, MGC13613, ESI, cemento...)

Name: Anti-Elafin Antibody (7F242)
Brand: TargetMol
SKU: TMAY-02271
Rating: 4.5 (1 reviews)

Catalog No. TMAY-02271 Copy Product Info

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Anti-Elafin Antibody (7F242) is a Rabbit antibody targeting Elafin. Anti-Elafin Antibody (7F242) can be used in ELISA.

Anti-Elafin Antibody (7F242)

Copy Product Info

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Catalog No. TMAY-02271

Synonyms WFDC14, WAP3, SKALP, peptidase inhibitor 3, MGC13613, ESI, cementoin

Anti-Elafin Antibody (7F242) is a Rabbit antibody targeting Elafin. Anti-Elafin Antibody (7F242) can be used in ELISA.

Anti-Elafin Antibody
(7F242)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$270	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description	Anti-Elafin Antibody (7F242) is a Rabbit antibody targeting Elafin. Anti-Elafin Antibody (7F242) can be used in ELISA.
Synonyms	WFDC14, WAP3, SKALP, peptidase inhibitor 3, MGC13613, ESI, cementoin
Ig Type	Rabbit IgG
Clone	7F242
Reactivity	Human
Specificity	Human Elafin No cross-reactivity in ELISA with Human SLPI Human TGM2
Application	ELISA
Recommended Dose	ELISA: 1:5000-1:10000
Antibody Type	Monoclonal
Host Species	Rabbit
Construction	This antibody was obtained from a rabbit immunized with purified, recombinant Human PI3 / Elafin / WFDC14 (rh PI3 / Elafin / WFDC14; TMPY-01909; NP_002629.1; Met1-Gln117).
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Elafin, also known as Elastase-specific inhibitor, Peptidase inhibitor 3, Protease inhibitor WAP3, Skin-derived antileukoproteinase, WAP four-disulfide core domain protein 14, PI3, WAP3 and WFDC14, is a secreted protein that contains one WAP domain. Elafin / PI3 consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain at the N-terminus serves as an anchor to localize elafin covalently to specific sites on extracellular matrix proteins. The serine anti-protease Elafin / PI3 is expressed by monocytes, alveolar macrophages, neutrophils, and at mucosal surfaces and possesses antimicrobial activity. It is also known to reduce lipopolysaccharide-induced neutrophil influx into murine alveoli as well as to abrogate lipopolysaccharide-induced production of matrix metalloprotease 9, macrophage inhibitory protein 2, and tumor necrosis factor-alpha by as-yet unidentified mechanisms. Elafin / PI3 is a neutrophil serine protease inhibitor expressed in lung and displaying anti-inflammatory and anti-bacterial properties. Elafin / PI3 is a neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis. Elafin / PI3 will regulate proteolytic enzymes during menstruation and will contribute to the innate defense against uterine infection.

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Human PI3 / Elafin / WFDC14 protein (TMPY-01909)
Antigen Species	Human
Biology Area	Serine Proteases and Regulators

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

WFDC-14WFDC 14WAP-3WAP 3MGC-13613MGC 13613

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