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Danofloxacin mesylate

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Catalog No. T1276Cas No. 119478-55-6
Alias CP 76136-27

Danofloxacin mesylate (CP 76136-27) is a synthetic antibacterial agent of the fluoroquinolone class that primarily inhibits bacterial DNA-gyrase.

Danofloxacin mesylate
Other Forms of Danofloxacin mesylate:

Danofloxacin mesylate

🥰Excellent
Purity: 99.73%
Catalog No. T1276Alias CP 76136-27Cas No. 119478-55-6
Danofloxacin mesylate (CP 76136-27) is a synthetic antibacterial agent of the fluoroquinolone class that primarily inhibits bacterial DNA-gyrase.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mg$31In StockIn Stock
100 mg$51In StockIn Stock
500 mg$152-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.73%
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Product Introduction

Bioactivity
Description
Danofloxacin mesylate (CP 76136-27) is a synthetic antibacterial agent of the fluoroquinolone class that primarily inhibits bacterial DNA-gyrase.
In vitro
In vivo, Danofloxacin demonstrates a protective effect against Pasteurella multocida (PD50=0.38 mg/kg), Escherichia coli (PD50=0.8 mg/kg), and Salmonella Choleraesuis (PD50=2.42 mg/kg) in mice.
In vivo
Danofloxacin exhibits a minimum inhibitory concentration (MIC90) of 0.125μg/ml against isolates of Pasteurella haemolytica, Pasteurella multocida, and Haemophilus somnus from both Europe and North America.
SynonymsCP 76136-27
Chemical Properties
Molecular Weight453.48
FormulaC19H20FN3O3·CH4O3S
Cas No.119478-55-6
SmilesO=S(=O)(C)O.C1CC1n1c2cc(c(cc2c(=O)c(c1)C(=O)O)F)N1[C@@H]2CN([C@H](C1)C2)C
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 4.6 mg/mL (10.14 mM), Sonication and heating are recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (2.21 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2052 mL11.0258 mL22.0517 mL110.2584 mL
5 mM0.4410 mL2.2052 mL4.4103 mL22.0517 mL
10 mM0.2205 mL1.1026 mL2.2052 mL11.0258 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

RNASynthesisRNA SynthesisInhibitorinhibitDNASynthesisDNA-gyraseDNA SynthesisDanofloxacin mesylateDanofloxacin MesylateDanofloxacinBacterialAntibiotic
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