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WAY-200070

Name: WAY-200070
Brand: TargetMol
SKU: T3958
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3958Cas No. 440122-66-7

Alias WAY 200070

WAY-200070 is a specific agonist of estrogen receptor β (ERRβ, IC50: 2.3 nM).

WAY-200070

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Purity: 99.75%

Catalog No. T3958Alias WAY 200070Cas No. 440122-66-7

WAY-200070 is a specific agonist of estrogen receptor β (ERRβ, IC50: 2.3 nM).

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$35	In Stock	In Stock
5 mg	$56	In Stock	In Stock
10 mg	$97	In Stock	In Stock
25 mg	$198	In Stock	In Stock
50 mg	$328	In Stock	In Stock
100 mg	$529	-	In Stock
200 mg	$753	-	In Stock
1 mL x 10 mM (in DMSO)	$62	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.75%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	WAY-200070 is a specific agonist of estrogen receptor β (ERRβ, IC50: 2.3 nM).
Targets&IC50	ERRβ:2.3 nM, ERα:155 nM
In vivo	In vivo, it is commonly added covalently to the N-terminus of proteins in a co-translational process termed N-myristoylation. In addition, there are examples where N-myristoylation occurs post-translationally, when a hidden myristoylation pattern is exposed.
Synonyms	WAY 200070

Chemical Properties

Molecular Weight	306.11
Formula	C₁₃H₈BrNO₃
Cas No.	440122-66-7
Smiles	BrC1=C2C(N=C(O2)C3=CC=C(O)C=C3)=CC(O)=C1
Relative Density.	1.720 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (163.34 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2668 mL	16.3340 mL	32.6680 mL	163.3400 mL
5 mM	0.6534 mL	3.2668 mL	6.5336 mL	32.6680 mL
10 mM	0.3267 mL	1.6334 mL	3.2668 mL	16.3340 mL
20 mM	0.1633 mL	0.8167 mL	1.6334 mL	8.1670 mL
50 mM	0.0653 mL	0.3267 mL	0.6534 mL	3.2668 mL
100 mM	0.0327 mL	0.1633 mL	0.3267 mL	1.6334 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc