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Fmoc-D-Cha-OH

Name: Fmoc-D-Cha-OH
Brand: TargetMol
SKU: T66703
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T66703Cas No. 144701-25-7

Fmoc-D-Cha-OH (FDCO) is an apoptotic DNase γ inhibitor that inhibits the release of HMGB1.

Fmoc-D-Cha-OH

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Purity: 98.62%

Catalog No. T66703Cas No. 144701-25-7

Fmoc-D-Cha-OH (FDCO) is an apoptotic DNase γ inhibitor that inhibits the release of HMGB1.

Pack Size	Price	Availability	Quantity
1 g	$29	In Stock

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Batch Information

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Purity:98.62%

Resource Download

COA HNMR HPLC MS

Product Introduction

Bioactivity

Description

Fmoc-D-Cha-OH (FDCO) is an apoptotic DNase γ inhibitor that inhibits the release of HMGB1.

Chemical Properties

Molecular Weight	393.48
Formula	C₂₄H₂₇NO₄
Cas No.	144701-25-7
Smiles	OC(=O)[C@@H](CC1CCCCC1)NC(=O)OCC1c2ccccc2-c2ccccc12
Color	White
Appearance	Solid
Sequence	Fmoc-D-Cha-OH
Sequence Short	X

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (203.31 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5414 mL	12.7071 mL	25.4143 mL	127.0713 mL
5 mM	0.5083 mL	2.5414 mL	5.0829 mL	25.4143 mL
10 mM	0.2541 mL	1.2707 mL	2.5414 mL	12.7071 mL
20 mM	0.1271 mL	0.6354 mL	1.2707 mL	6.3536 mL
50 mM	0.0508 mL	0.2541 mL	0.5083 mL	2.5414 mL
100 mM	0.0254 mL	0.1271 mL	0.2541 mL	1.2707 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc