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6-Aminochrysene (Synonyms: 6-Chrysenamine)

Catalog No. T13519 Copy Product Info
Purity: 99.55%
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6-Aminochrysene (6-Chrysenamine) is an inhibitor of the growth of several solid experimental tumors and can be used in studies about splenomegaly, breast cancer and myeloid leukemia.

6-Aminochrysene

Copy Product Info
🥰Excellent
Catalog No. T13519
Synonyms 6-Chrysenamine

6-Aminochrysene (6-Chrysenamine) is an inhibitor of the growth of several solid experimental tumors and can be used in studies about splenomegaly, breast cancer and myeloid leukemia.

6-Aminochrysene
Cas No. 2642-98-0
Pack SizePriceUSA StockGlobal StockQuantity
10 mg$29-In Stock
25 mgPreferential-In Stock
50 mgPreferential-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.55%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
6-Aminochrysene (6-Chrysenamine) is an inhibitor of the growth of several solid experimental tumors and can be used in studies about splenomegaly, breast cancer and myeloid leukemia.
In vivo
6-Aminochrysene inhibited the hydroxylation of aniline, O-demethylation of p-nitroanisole, and N-demethylation of aminopyrine by rat liver microsomes[1].
Animal Research
In Male CD rats, intraperitoneal injections of 6-Aminochrysene with 25, 50, and 100 mg/kg are pre-treated once daily for 3 consecutive days before sacrifice[1].
Synonyms6-Chrysenamine
Chemical Properties
Molecular Weight243.3
FormulaC18H13N
Cas No.2642-98-0
SmilesNc1cc2c3ccccc3ccc2c2ccccc12
Relative Density.0.8933 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 90 mg/mL (369.91 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (13.56 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.1102 mL20.5508 mL41.1015 mL205.5076 mL
5 mM0.8220 mL4.1102 mL8.2203 mL41.1015 mL
10 mM0.4110 mL2.0551 mL4.1102 mL20.5508 mL
20 mM0.2055 mL1.0275 mL2.0551 mL10.2754 mL
50 mM0.0822 mL0.4110 mL0.8220 mL4.1102 mL
100 mM0.0411 mL0.2055 mL0.4110 mL2.0551 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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