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BMS-593214

🥰Excellent
Catalog No. T71641Cas No. 1004551-40-9
Alias BMS593214, BMS 593214

BMS-593214 is an active site-directed factor (F) VIIa inhibitor that exhibits antithrombotic and antihaemostatic properties. It acts as a direct competitive inhibitor of human FVIIa and a non-competitive inhibitor of FVIIa-activated substrate FX. Additionally, BMS-593214 effectively prevents electroinduced carotid artery thrombosis (AT) and wire-induced vena cava thrombosis (VT).

BMS-593214

BMS-593214

🥰Excellent
Purity: 98.04%
Catalog No. T71641Alias BMS593214, BMS 593214Cas No. 1004551-40-9
BMS-593214 is an active site-directed factor (F) VIIa inhibitor that exhibits antithrombotic and antihaemostatic properties. It acts as a direct competitive inhibitor of human FVIIa and a non-competitive inhibitor of FVIIa-activated substrate FX. Additionally, BMS-593214 effectively prevents electroinduced carotid artery thrombosis (AT) and wire-induced vena cava thrombosis (VT).
Pack SizePriceAvailabilityQuantity
1 mg$297In Stock
5 mg$745In Stock
10 mg$1,120In Stock
25 mg$1,670In Stock
50 mg$2,180In Stock
100 mg$2,800In Stock
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:98.04%
ee:100%
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COA CSFC HNMR LCMS

Product Introduction

Bioactivity
Description
BMS-593214 is an active site-directed factor (F) VIIa inhibitor that exhibits antithrombotic and antihaemostatic properties. It acts as a direct competitive inhibitor of human FVIIa and a non-competitive inhibitor of FVIIa-activated substrate FX. Additionally, BMS-593214 effectively prevents electroinduced carotid artery thrombosis (AT) and wire-induced vena cava thrombosis (VT).
SynonymsBMS593214, BMS 593214
Chemical Properties
Molecular Weight505.56
FormulaC31H27N3O4
Cas No.1004551-40-9
SmilesC(=N)(N)C=1C=C2[C@@]3([C@]([C@@H](NC2=CC1)C4=C(C=C(O)C(OC)=C4)C5=CC=C(C(O)=O)C=C5)(CC=6C3=CC=CC6)[H])[H]
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (158.24 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9780 mL9.8900 mL19.7800 mL98.9002 mL
5 mM0.3956 mL1.9780 mL3.9560 mL19.7800 mL
10 mM0.1978 mL0.9890 mL1.9780 mL9.8900 mL
20 mM0.0989 mL0.4945 mL0.9890 mL4.9450 mL
50 mM0.0396 mL0.1978 mL0.3956 mL1.9780 mL
100 mM0.0198 mL0.0989 mL0.1978 mL0.9890 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Keywords

FG-7080FG7080coagulation factor VIIaBMS-593214
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