Shopping Cart

Your shopping cart is currently empty

7-Ethoxy-4-Methylcoumarin

Name: 7-Ethoxy-4-Methylcoumarin
Brand: TargetMol
SKU: T8038
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T8038Cas No. 87-05-8

7-Ethoxy-4-Methylcoumarin is considered an inhibitor of enzymes in cells and has been used in studies of enzyme inhibition and has been used to study the effects of various drugs on the human body.

7-Ethoxy-4-Methylcoumarin

Copy Product Info

😃Good

Purity: 99.50%

Catalog No. T8038Cas No. 87-05-8

7-Ethoxy-4-Methylcoumarin is considered an inhibitor of enzymes in cells and has been used in studies of enzyme inhibition and has been used to study the effects of various drugs on the human body.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
200 mg	$29	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.50%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

7-Ethoxy-4-Methylcoumarin AI Summary

7-Ethoxy-4-Methylcoumarin exhibits significant biological activities across multiple applications. It shows potent growth inhibition activity against various human tumor cell lines, including breast, renal, lung, prostate, central nervous system, leukemia, ovarian, melanoma, and colon cancers, with a consistent GI50 value of 100,000 nM. Additionally, it demonstrates antiasthmatic activity by reversing carbachol-induced contraction in Wistar rat tracheal rings, achieving a maximum effect (Emax) of 100% at concentrations ranging from 0.1 to 500 µM and an EC50 value of 80,000 nM. In terms of metabolism, 7-Ethoxy-4-Methylcoumarin exhibits high intrinsic clearance in human liver microsomes with a clearance rate of 325 mL·min⁻¹·kg⁻¹ and a short half-life of 0.064 hours, indicating efficient liver metabolism..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

7-Ethoxy-4-Methylcoumarin is considered an inhibitor of enzymes in cells and has been used in studies of enzyme inhibition and has been used to study the effects of various drugs on the human body.

Chemical Properties

Molecular Weight	204.22
Formula	C₁₂H₁₂O₃
Cas No.	87-05-8
Smiles	CCOC1=CC=C2C(C)=CC(=O)OC2=C1
Relative Density.	1.163 g/cm3

Storage & Solubility Information

Storage

store under nitrogen,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25 mg/mL (122.42 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.8967 mL	24.4834 mL	48.9668 mL	244.8340 mL
5 mM	0.9793 mL	4.8967 mL	9.7934 mL	48.9668 mL
10 mM	0.4897 mL	2.4483 mL	4.8967 mL	24.4834 mL
20 mM	0.2448 mL	1.2242 mL	2.4483 mL	12.2417 mL
50 mM	0.0979 mL	0.4897 mL	0.9793 mL	4.8967 mL
100 mM	0.0490 mL	0.2448 mL	0.4897 mL	2.4483 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc