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TC HSD 21

Name: TC HSD 21
Brand: TargetMol
SKU: T13100
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T13100Cas No. 330203-01-5

TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).

TC HSD 21

🥰Excellent

Purity: 98.5%

Catalog No. T13100Cas No. 330203-01-5

TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).

Pack Size	Price	Availability
1 mg	$35	In Stock
5 mg	$83	In Stock
10 mg	$139	In Stock
25 mg	$251	In Stock
50 mg	$363	In Stock
100 mg	$487	In Stock
200 mg	$657	In Stock
1 mL x 10 mM (in DMSO)	$92	In Stock

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Batch Information

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Purity:98.5%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).
Targets&IC50	17β-HSD3:14 nM

Chemical Properties

Molecular Weight	422.32
Formula	C₁₇H₁₂BrNO₃S₂
Cas No.	330203-01-5
Smiles	COc1ccc(cc1)N1C(=S)S\C(=C/c2ccc(O)c(Br)c2)C1=O
Relative Density.	1.72 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 225 mg/mL (532.77 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3679 mL	11.8394 mL	23.6787 mL	118.3936 mL
5 mM	0.4736 mL	2.3679 mL	4.7357 mL	23.6787 mL
10 mM	0.2368 mL	1.1839 mL	2.3679 mL	11.8394 mL
20 mM	0.1184 mL	0.5920 mL	1.1839 mL	5.9197 mL
50 mM	0.0474 mL	0.2368 mL	0.4736 mL	2.3679 mL
100 mM	0.0237 mL	0.1184 mL	0.2368 mL	1.1839 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc