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Luliconazole

Name: Luliconazole
Brand: TargetMol
SKU: T2411
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2411Cas No. 187164-19-8

Alias NND 502

Luliconazole (NND 502) is an Azole Antifungal. The mechanism of action of luliconazole is as a Cytochrome P450 2C19 Inhibitor.

Luliconazole

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Purity: 99.83%

Catalog No. T2411Alias NND 502Cas No. 187164-19-8

Luliconazole (NND 502) is an Azole Antifungal. The mechanism of action of luliconazole is as a Cytochrome P450 2C19 Inhibitor.

Pack Size	Price	Availability
50 mg	$30	In Stock
100 mg	$42	In Stock
500 mg	$98	In Stock
1 g	$153	In Stock
1 mL x 10 mM (in DMSO)	$32	In Stock

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Purity:99.83%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Luliconazole (NND 502) is an Azole Antifungal. The mechanism of action of luliconazole is as a Cytochrome P450 2C19 Inhibitor.
In vitro	Luliconazole inhibits the growth of all filamentous fungi (except Saccharomyces cerevisiae) (MIC,≦0.004-0.125 μg/ml), Candida albicans (MIC range: 0.031-0.13 mg/ml), Trichophyton rubrum (MIC,≦0.00012-0.002 mg/ml).
In vivo	Luliconazole inhibits the growth of all filamentous fungi (except Saccharomyces cerevisiae) (MIC,≦0.004-0.125 μg/ml), Candida albicans (MIC range: 0.031-0.13 mg/ml), Trichophyton rubrum (MIC,≦0.00012-0.002 mg/ml).
Synonyms	NND 502

Chemical Properties

Molecular Weight	354.28
Formula	C₁₄H₉Cl₂N₃S₂
Cas No.	187164-19-8
Smiles	Clc1ccc([C@@H]2CS\C(S2)=C(\C#N)n2ccnc2)c(Cl)c1
Relative Density.	1.52 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 66 mg/mL (186.29 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

Ethanol: 5 mg/mL (14.11 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.65 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8226 mL	14.1131 mL	28.2263 mL	141.1313 mL
5 mM	0.5645 mL	2.8226 mL	5.6453 mL	28.2263 mL
10 mM	0.2823 mL	1.4113 mL	2.8226 mL	14.1131 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.1411 mL	0.7057 mL	1.4113 mL	7.0566 mL
50 mM	0.0565 mL	0.2823 mL	0.5645 mL	2.8226 mL
100 mM	0.0282 mL	0.1411 mL	0.2823 mL	1.4113 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc