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Carbenicillin disodium

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Catalog No. T1143Cas No. 4800-94-6
Alias Sodium carbenicillin, BRL-2064

Carbenicillin disodium (BRL-2064) is a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity.

Carbenicillin disodium

Carbenicillin disodium

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Purity: 99.77%
Catalog No. T1143Alias Sodium carbenicillin, BRL-2064Cas No. 4800-94-6
Carbenicillin disodium (BRL-2064) is a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
200 mg$30In StockIn Stock
500 mg$44In StockIn Stock
1 g$48In StockIn Stock
5 g$123-In Stock
10 g$172-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.77%
Potency:750 mcg/mg
Color:White to Yellow
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Product Introduction

Bioactivity
Description
Carbenicillin disodium (BRL-2064) is a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity.
In vitro
In patients with cystic fibrosis, Carbenicillin (0.1μg/mL) exhibited no hypersensitivity drug reactions as measured by antibody levels. In chrysanthemums and TOBC, Carbenicillin (50 μg/mL) induced phytotoxicity in a concentration-dependent manner.
In vivo
Carbenicillin (125 mg/L) effectively suppresses the proliferation of soil bacteria, increases the volume of somatic embryos, and the number of somatic embryos per callus tissue. Within the callus tissue, Carbenicillin at concentrations of 250 mg/L to 500 mg/L can enhance the fresh weight of the tissue. At a higher concentration of 1 g/L, Carbenicillin reduces the germination frequency of leaf disc explants. Additionally, in vitro exposure of patients' isolated leukocytes to Carbenicillin (0.1 g/ml) does not result in histamine release.
SynonymsSodium carbenicillin, BRL-2064
Chemical Properties
Molecular Weight422.36
FormulaC17H16N2Na2O6S
Cas No.4800-94-6
Smiles[Na+].[C@H]1(C(=O)N2[C@@H]1SC([C@@H]2C(=O)[O-])(C)C)NC(=O)C(C(=O)[O-])c1ccccc1.[Na+]
Relative Density.no data available
Storage & Solubility Information
StorageThe compound is unstable in solution. Please use soon | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: < 1 mg/mL (insoluble), The compound is unstable in solution, please use soon.
Ethanol: < 1 mg/mL (insoluble or slightly soluble), The compound is unstable in solution, please use soon.
DMSO: 62.5 mg/mL (147.98 mM), Sonication is recommended. The compound is unstable in solution, please use soon.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.74 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3676 mL11.8382 mL23.6765 mL118.3824 mL
5 mM0.4735 mL2.3676 mL4.7353 mL23.6765 mL
10 mM0.2368 mL1.1838 mL2.3676 mL11.8382 mL
20 mM0.1184 mL0.5919 mL1.1838 mL5.9191 mL
50 mM0.0474 mL0.2368 mL0.4735 mL2.3676 mL
100 mM0.0237 mL0.1184 mL0.2368 mL1.1838 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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