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Glufosinate ammonium

Name: Glufosinate ammonium
Brand: TargetMol
SKU: T15391
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T15391Cas No. 77182-82-2

Glufosinate ammonium is a phosphinic acid analogue of glutamic acid and is an herbicide. Glufosinate ammonium is converted by plant cells into PT (L-phosphinothricin). Glufosinate ammonium has neurotoxic activity.

Glufosinate ammonium

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Purity: 99.93%

Catalog No. T15391Cas No. 77182-82-2

Pack Size	Price	USA Warehouse	Global Warehouse
100 mg	$31	In Stock	In Stock
500 mg	$70	In Stock	In Stock
1 g	$103	In Stock	In Stock
5 g	$255	In Stock	In Stock
10 g	$378	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:99.93%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Glufosinate ammonium is a phosphinic acid analogue of glutamic acid and is an herbicide. Glufosinate ammonium is converted by plant cells into PT (L-phosphinothricin). Glufosinate ammonium has neurotoxic activity.
In vitro	Glufosinate ammonium impairs ependymal cell capability to synthetize cilia. Glufosinate ammonium (1-100 μM; 12DIV) obviously reduces Celsr2 gene expression at 100 μM. Glufosinate ammonium (1-100 μM; 12DIV) disrupts cell-cell adhesion in differentiated V-SVZ neural stem cells (NSCs) [2].
In vivo	Glufosinate ammonium (10-250 mg/kg; gavage; daily; on days 6-15 of gestation) exhibits maternal toxicity at doses of 50 or 250 mg/kg in Wistar rats. In both male and female rats, the elimination of Glufosinate ammonium (oral intubation) from the blood has a half-life of less than 4 hours [3].

Chemical Properties

Molecular Weight	198.16
Formula	C₅H₁₅N₂O₄P
Cas No.	77182-82-2
Smiles	CP(O)(CCC(C([O-])=O)N)=O.[NH4+]
Relative Density.	1.4 g/cm3

Storage & Solubility Information

Storage

keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 262.5 mg/mL (1324.69 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	5.0464 mL	25.2321 mL	50.4643 mL	252.3214 mL
5 mM	1.0093 mL	5.0464 mL	10.0929 mL	50.4643 mL
10 mM	0.5046 mL	2.5232 mL	5.0464 mL	25.2321 mL
20 mM	0.2523 mL	1.2616 mL	2.5232 mL	12.6161 mL
50 mM	0.1009 mL	0.5046 mL	1.0093 mL	5.0464 mL
100 mM	0.0505 mL	0.2523 mL	0.5046 mL	2.5232 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc