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LYN-1604

Name: LYN-1604
Brand: TargetMol
SKU: T4123
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4123Cas No. 2088939-99-3

Alias LYN1604

LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.

LYN-1604

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Catalog No. T4123Alias LYN1604Cas No. 2088939-99-3

LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$31	In Stock	-
5 mg	$71	In Stock	-
10 mg	$113	In Stock	-
25 mg	$228	In Stock	-
50 mg	$347	In Stock	-
1 mL x 10 mM (in DMSO)	$98	In Stock	-

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
Targets&IC50	ULK1:18.94 nM(EC50)
Synonyms	LYN1604

Chemical Properties

Molecular Weight	584.62
Formula	C₃₃H₄₃Cl₂N₃O₂
Cas No.	2088939-99-3
Smiles	C(CN1CCN(C(CN(CC(C)C)CC(C)C)=O)CC1)(OCC2=CC3=C(C=C2)C=CC=C3)C4=C(Cl)C=C(Cl)C=C4
Relative Density.	1.168 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 46 mg/mL (78.68 mM), Sonication is recommended.

H2O: 90 mg/mL (153.95 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	1.7105 mL	8.5526 mL	17.1051 mL	85.5256 mL
5 mM	0.3421 mL	1.7105 mL	3.4210 mL	17.1051 mL
10 mM	0.1711 mL	0.8553 mL	1.7105 mL	8.5526 mL
20 mM	0.0855 mL	0.4276 mL	0.8553 mL	4.2763 mL
50 mM	0.0342 mL	0.1711 mL	0.3421 mL	1.7105 mL

H2O

	1mg	5mg	10mg	50mg
100 mM	0.0171 mL	0.0855 mL	0.1711 mL	0.8553 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc