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Anti-Mouse IL-1a Antibody (ALF-161)
Catalog No. T80586 Copy Product Info
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Anti-Mouse IL-1a Antibody (ALF-161) is a monoclonal antibody inhibitor targeting mouse IL-1α. It can block IL-1α signaling, thereby inhibiting CD8+ T cell responses and reversing myeloid cell expansion, and can be used in the research of immune diseases and cancer.
Anti-Mouse IL-1a Antibody (ALF-161)
Copy Product Info🥰Excellent
Catalog No. T80586
Anti-Mouse IL-1a Antibody (ALF-161) is a monoclonal antibody inhibitor targeting mouse IL-1α. It can block IL-1α signaling, thereby inhibiting CD8+ T cell responses and reversing myeloid cell expansion, and can be used in the research of immune diseases and cancer.
Anti-Mouse IL-1a Antibody
(ALF-161)
(ALF-161)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $149 | - | In Stock | |
| 5 mg | $539 | - | In Stock | |
| 10 mg | $868 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:>95.0% (SDS-PAGE); 100% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Anti-Mouse IL-1a Antibody (ALF-161) is a monoclonal antibody inhibitor targeting mouse IL-1α. It can block IL-1α signaling, thereby inhibiting CD8+ T cell responses and reversing myeloid cell expansion, and can be used in the research of immune diseases and cancer. |
| In vitro | In C57BL/6J mice injected with adeno-associated virus ovalbumin (AAV-OVA), Anti-Mouse IL-1a Antibody (ALF-161) (200 μg, intraperitoneal injection, twice weekly for 4 weeks) suppressed CD8+ T cell responses[1]. In wild-type female C57BL/6 mice bearing AT3 tumors, Anti-Mouse IL-1a Antibody (ALF-161) (200 µg, intraperitoneal injection, every 3 days, repeated multiple times) reversed myeloid cell expansion and improved T cell function[2]. |
| Clone | ALF-161 |
| Reactivity | Mouse |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | IL-1a |
| Molecular Weight | ~150 kDa |
| Isotype | Armenian Hamster IgG |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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