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Benserazide hydrochloride

🥰Excellent
Catalog No. T1517Cas No. 14919-77-8
Alias Serazide, Ro 4-4602, Benserazide HCl

Benserazide hydrochloride (Ro 4-4602) is a peripherally-acting L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.

Benserazide hydrochloride
Other Forms of Benserazide hydrochloride:

Benserazide hydrochloride

🥰Excellent
Purity: 99.74%
Catalog No. T1517Alias Serazide, Ro 4-4602, Benserazide HClCas No. 14919-77-8
Benserazide hydrochloride (Ro 4-4602) is a peripherally-acting L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.
Pack SizePriceAvailabilityQuantity
500 mg$46In Stock
1 g$61In Stock
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Purity:99.74%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Benserazide hydrochloride (Ro 4-4602) is a peripherally-acting L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.
SynonymsSerazide, Ro 4-4602, Benserazide HCl
Chemical Properties
Molecular Weight293.7
FormulaC10H15N3O5·HCl
Cas No.14919-77-8
Smilesc1(c(c(c(cc1)O)O)O)CNNC(=O)C(CO)N.Cl
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 1 mg/mL (3.4 mM), Heating is recommended.
DMSO: 40 mg/mL (136.19 mM), Sonication is recommended.(The compound is unstable in solution, please use soon.)
H2O: 53 mg/mL (180.46 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.81 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
Ethanol/DMSO/H2O
1mg5mg10mg50mg
1 mM3.4048 mL17.0242 mL34.0483 mL170.2417 mL
DMSO/H2O
1mg5mg10mg50mg
5 mM0.6810 mL3.4048 mL6.8097 mL34.0483 mL
10 mM0.3405 mL1.7024 mL3.4048 mL17.0242 mL
20 mM0.1702 mL0.8512 mL1.7024 mL8.5121 mL
50 mM0.0681 mL0.3405 mL0.6810 mL3.4048 mL
100 mM0.0340 mL0.1702 mL0.3405 mL1.7024 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

DopamineReceptorDopamine ReceptorDopamineDOPA decarboxylaseBenserazide
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