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LY450108

🥰Excellent
Catalog No. TQ0289Cas No. 376594-67-1

LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.

LY450108

LY450108

🥰Excellent
Purity: 99.71%
Catalog No. TQ0289Cas No. 376594-67-1
LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.
Pack SizePriceAvailabilityQuantity
5 mg$37In Stock
10 mg$60In Stock
25 mg$103In Stock
50 mg$156In Stock
1 mL x 10 mM (in DMSO)$41In Stock
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:99.71%
ee:97.94%
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Product Introduction

Bioactivity
Description
LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.
Chemical Properties
Molecular Weight396.45
FormulaC19H22F2N2O3S
Cas No.376594-67-1
SmilesCC(C)S(=O)(=O)NC[C@H](C)c1ccc(NC(=O)c2cc(F)cc(F)c2)cc1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (126.12 mM), Sonication is recommended.
H2O: 1 mg/mL (2.52 mM), Sonication and heating are recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.5224 mL12.6119 mL25.2239 mL126.1193 mL
DMSO
1mg5mg10mg50mg
5 mM0.5045 mL2.5224 mL5.0448 mL25.2239 mL
10 mM0.2522 mL1.2612 mL2.5224 mL12.6119 mL
20 mM0.1261 mL0.6306 mL1.2612 mL6.3060 mL
50 mM0.0504 mL0.2522 mL0.5045 mL2.5224 mL
100 mM0.0252 mL0.1261 mL0.2522 mL1.2612 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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