Shopping Cart

Your shopping cart is currently empty

Idramantone

Name: Idramantone
Brand: TargetMol
SKU: T1588
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T1588Cas No. 20098-14-0

Alias Kemantane, 5-Hydroxy-2-adamantanone

Idramantone (Kemantane) is an immune agonist.

Idramantone

Copy Product Info

😃Good

Purity: 99.25%

Catalog No. T1588Alias Kemantane, 5-Hydroxy-2-adamantanoneCas No. 20098-14-0

Idramantone (Kemantane) is an immune agonist.

Pack Size	Price	USA Warehouse	Global Warehouse
200 mg	$31	In Stock	In Stock
500 mg	$48	In Stock	In Stock
1 g	$70	In Stock	In Stock
5 g	$168	-	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.25%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Idramantone (Kemantane) is an immune agonist.
Kinase Assay	Assays with human placental aromatase: Microsomes are prepared from human placenta and stored at -80℃. The rate of aromatization is determined by measuring the tritiated water released from [1β-3H]A. The assay is carried out in a final volume of 1 mL, in 10 mM phosphate buffer, pH 7.5, containing 100 mM KCl, 1 mM EDTA, 1 mM dithiothreitol, 100 μM NADPH, the enzyme preparation and the appropriate concentrations of Exemestane (in duplicate) and the substrate. After a 10 min incubation at 37 ℃, the assay is terminated by the addition of 4 mL cold chloroform. The acqueous phase is treated with a charcoal suspension, the supernatant is removed and counted for radioactivity by liquid scintillation in Rialuma. For the determination of the IC50 values, various concentrations of Exemestane are incubated with 20 μg of microsomal protein, in the presence of a fixed amount (50 nM) of [3H]A.
Synonyms	Kemantane, 5-Hydroxy-2-adamantanone

Chemical Properties

Molecular Weight	166.22
Formula	C₁₀H₁₄O₂
Cas No.	20098-14-0
Smiles	OC12CC3CC(C1)C(=O)C(C3)C2
Relative Density.	1.301g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 31 mg/mL (186.5 mM), Sonication is recommended.

H2O: 30 mg/mL (180.48 mM), Sonication is recommended.

DMSO: 45 mg/mL (270.73 mM), Sonication is recommended.

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	6.0161 mL	30.0806 mL	60.1612 mL	300.8062 mL
5 mM	1.2032 mL	6.0161 mL	12.0322 mL	60.1612 mL
10 mM	0.6016 mL	3.0081 mL	6.0161 mL	30.0806 mL
20 mM	0.3008 mL	1.5040 mL	3.0081 mL	15.0403 mL
50 mM	0.1203 mL	0.6016 mL	1.2032 mL	6.0161 mL
100 mM	0.0602 mL	0.3008 mL	0.6016 mL	3.0081 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc