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Lycorine hydrochloride

Name: Lycorine hydrochloride
Brand: TargetMol
SKU: T2774
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T2774Cas No. 2188-68-3

Alias Narcissine hydrochloride, Lycorine chloride, Licorine hydrochloride, Galanthidine hydrochloride, Amarylline hydrochloride

Lycorine hydrochloride (Narcissine hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity.

Lycorine hydrochloride

🥰Excellent

Purity: 99.49%

Catalog No. T2774Alias Narcissine hydrochloride, Lycorine chloride, Licorine hydrochloride, Galanthidine hydrochloride, Amarylline hydrochlorideCas No. 2188-68-3

Lycorine hydrochloride (Narcissine hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity.

Pack Size	Price	Availability
25 mg	$39	In Stock
50 mg	$64	In Stock
100 mg	$97	In Stock
500 mg	$238	In Stock
1 mL x 10 mM (in DMSO)	$43	In Stock

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Purity:99.49%

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	Lycorine hydrochloride (Narcissine hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity.
Targets&IC50	VE cadherin:1.2 μM
Synonyms	Narcissine hydrochloride, Lycorine chloride, Licorine hydrochloride, Galanthidine hydrochloride, Amarylline hydrochloride

Chemical Properties

Molecular Weight	323.77
Formula	C₁₆H₁₈ClNO₄
Cas No.	2188-68-3
Smiles	Cl.O[C@H]1C=C2CCN3Cc4cc5OCOc5cc4[C@@H]([C@@H]23)[C@@H]1O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (154.43 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.18 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0886 mL	15.4431 mL	30.8861 mL	154.4306 mL
5 mM	0.6177 mL	3.0886 mL	6.1772 mL	30.8861 mL
10 mM	0.3089 mL	1.5443 mL	3.0886 mL	15.4431 mL
20 mM	0.1544 mL	0.7722 mL	1.5443 mL	7.7215 mL
50 mM	0.0618 mL	0.3089 mL	0.6177 mL	3.0886 mL
100 mM	0.0309 mL	0.1544 mL	0.3089 mL	1.5443 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc