Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Zabedosertib (BAY 1834845) is an inhibitor of IRAK4 with immunomodulatory potential. Zabedosertib protects against acute respiratory distress syndrome, a new study suggests.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 60.00 | |
5 mg | In stock | $ 147.00 | |
10 mg | In stock | $ 229.00 | |
25 mg | In stock | $ 388.00 | |
50 mg | In stock | $ 566.00 | |
100 mg | In stock | $ 790.00 | |
500 mg | In stock | $ 1,620.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 162.00 |
Description | Zabedosertib (BAY 1834845) is an inhibitor of IRAK4 with immunomodulatory potential. Zabedosertib protects against acute respiratory distress syndrome, a new study suggests. |
Targets&IC50 | IRAK4:3.55 nM |
In vivo | In an inhaled lipopolysaccharide (LPS)-induced ARDS mouse model, BAY-1834845 downregulated genes more efficiently than dexamethasone, especially TNF, IL-17, interferon, and Toll-like receptor signaling[1]. |
Synonyms | BAY 1834845 |
Molecular Weight | 470.47 |
Formula | C20H21F3N4O4S |
CAS No. | 1931994-81-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 112.5 mg/mL (239.1 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Zabedosertib 1931994-81-8 Immunology/Inflammation NF-Κb IRAK BAY 1834845 BAY1834845 BAY-1834845 inhibitor inhibit