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Demecarium bromide

Name: Demecarium bromide
Brand: TargetMol
SKU: T7213
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T7213Cas No. 56-94-0

Alias BC-48

Demecarium bromide (BC-48) is a potent cholinesterase inhibitor,and is treatment glaucoma agent.

Demecarium bromide

🥰Excellent

Catalog No. T7213Alias BC-48Cas No. 56-94-0

Demecarium bromide (BC-48) is a potent cholinesterase inhibitor,and is treatment glaucoma agent.

Pack Size	Price	Availability
5 mg	$35	In Stock
10 mg	$50	In Stock
25 mg	$82	In Stock
50 mg	$115	In Stock
100 mg	$156	In Stock
1 mL x 10 mM (in DMSO)	$57	In Stock

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Product Introduction

Bioactivity

Description	Demecarium bromide (BC-48) is a potent cholinesterase inhibitor,and is treatment glaucoma agent.
Targets&IC50	ChE:0.15 μM (Kiapp)
Synonyms	BC-48

Chemical Properties

Molecular Weight	716.59
Formula	C₃₂H₅₂Br₂N₄O₄
Cas No.	56-94-0
Smiles	[Br-].[Br-].CN(CCCCCCCCCCN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C)C(=O)Oc1cccc(c1)[N+](C)(C)C
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 160 mg/mL (223.28 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3955 mL	6.9775 mL	13.9550 mL	69.7749 mL
5 mM	0.2791 mL	1.3955 mL	2.7910 mL	13.9550 mL
10 mM	0.1395 mL	0.6977 mL	1.3955 mL	6.9775 mL
20 mM	0.0698 mL	0.3489 mL	0.6977 mL	3.4887 mL
50 mM	0.0279 mL	0.1395 mL	0.2791 mL	1.3955 mL
100 mM	0.0140 mL	0.0698 mL	0.1395 mL	0.6977 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc