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Cudetaxestat

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Catalog No. T63190Cas No. 1782070-21-6
Alias BLD-0409

Cudetaxestat (BLD-0409) is a potent, orally active autotaxin inhibitor.

Cudetaxestat

Cudetaxestat

😃Good
Purity: 99.9%
Catalog No. T63190Alias BLD-0409Cas No. 1782070-21-6
Cudetaxestat (BLD-0409) is a potent, orally active autotaxin inhibitor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$70In StockIn Stock
5 mg$173In StockIn Stock
10 mg$260In StockIn Stock
25 mg$467In StockIn Stock
50 mg$696In StockIn Stock
100 mg$978In StockIn Stock
200 mg$1,290-In Stock
1 mL x 10 mM (in DMSO)$178In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.9%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Cudetaxestat (BLD-0409) is a potent, orally active autotaxin inhibitor.
SynonymsBLD-0409
Chemical Properties
Molecular Weight482.33
FormulaC21H15Cl2F2N3O2S
Cas No.1782070-21-6
SmilesCCCn1cc(cn1)-n1c(Cl)c(Sc2cccc(C(O)=O)c2F)c2ccc(Cl)c(F)c12
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 225 mg/mL (466.49 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0733 mL10.3663 mL20.7327 mL103.6635 mL
5 mM0.4147 mL2.0733 mL4.1465 mL20.7327 mL
10 mM0.2073 mL1.0366 mL2.0733 mL10.3663 mL
20 mM0.1037 mL0.5183 mL1.0366 mL5.1832 mL
50 mM0.0415 mL0.2073 mL0.4147 mL2.0733 mL
100 mM0.0207 mL0.1037 mL0.2073 mL1.0366 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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