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D-Glutamic acid

Name: D-Glutamic acid
Brand: TargetMol
SKU: T10935
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T10935Cas No. 6893-26-1

Alias (R)-Glutamic acid

D-Glutamic acid ((R)-Glutamic acid), the enantiomer of L-glutamic acid, is widely used in medicine and food.

D-Glutamic acid

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Purity: 99.33%

Catalog No. T10935Alias (R)-Glutamic acidCas No. 6893-26-1

D-Glutamic acid ((R)-Glutamic acid), the enantiomer of L-glutamic acid, is widely used in medicine and food.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	-	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.33%

Color:White

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COA LCMS

Product Introduction

Bioactivity

Description	D-Glutamic acid ((R)-Glutamic acid), the enantiomer of L-glutamic acid, is widely used in medicine and food.
In vitro	Various d-amino acids, such as D-serine, D-aspartic acid (D-Asp), and D-glutamic acid (D-Glu), are widely found in mammals, including humans, and are considered candidate new physiologically active substances and/or biomarkers. D-[Asp/Glu] (4 mg/mL) inhibited the binding of IgE to peanuts (75%), while D-Glu and D-Asp had no inhibitory effect. IgE is specific to D-[Asp/Glu] and may have the potential to remove IgE or reduce its binding to peanut allergens.
In vivo	At present, D-glutamic acid is receiving attention as a regulator of neuronal transmission and hormone secretion. It is only metabolized by D-aspartate oxidase in mammals. After intraperitoneal injection, L-glutamic acid is catabolized by α-ketoglutarate, and D-glutamic acid is converted to n-pyrrolidone carboxylic acid. The carbon 2 of D- and L-glutamic acid is converted to methyl acetate in the cecum. Both rat liver and kidney catalyze the conversion of D-glutamic acid to n-pyrrolidone carboxylic acid.
Synonyms	(R)-Glutamic acid

Chemical Properties

Molecular Weight	147.13
Formula	C₅H₉NO₄
Cas No.	6893-26-1
Smiles	[C@@H](CCC(O)=O)(C(O)=O)N
Relative Density.	1.5380 g/cm3

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 6.94 mg/mL (47.17 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	6.7967 mL	33.9836 mL	67.9671 mL	339.8355 mL
5 mM	1.3593 mL	6.7967 mL	13.5934 mL	67.9671 mL
10 mM	0.6797 mL	3.3984 mL	6.7967 mL	33.9836 mL
20 mM	0.3398 mL	1.6992 mL	3.3984 mL	16.9918 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc