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Sincalide

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Catalog No. TP1197Cas No. 25126-32-3
Alias SQ19844, Cholecystokinin octapeptide, CCK-8

Sincalide (CCK-8) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin.

Sincalide

Sincalide

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Purity: 98.32%
Catalog No. TP1197Alias SQ19844, Cholecystokinin octapeptide, CCK-8Cas No. 25126-32-3
Sincalide (CCK-8) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$225In StockIn Stock
2 mg$360In Stock-
5 mg$625In StockIn Stock
10 mg$1,000In Stock-
25 mg$1,750In Stock-
50 mg$2,800In Stock-
100 mgInquiryInquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.32%
Color:White
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Product Introduction

Bioactivity
Description
Sincalide (CCK-8) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin.
SynonymsSQ19844, Cholecystokinin octapeptide, CCK-8
Chemical Properties
Molecular Weight1143.27
FormulaC49H62N10O16S3
Cas No.25126-32-3
SmilesC([C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N)=O)=O)CC(O)=O)=O)CCSC)=O)NC(CNC([C@@H](NC([C@H](CC2=CC=C(OS(=O)(=O)O)C=C2)NC([C@H](CC(O)=O)N)=O)=O)CCSC)=O)=O)C=3C=4C(NC3)=CC=CC4
Relative Density.1.440 g/cm3 (Predicted)
SequenceAsp-{SO3H-Tyr}-Met-Gly-Trp-Met-Asp-Phe-NH2
Sequence ShortD-{SO3H-Tyr}-MGWMDF
Storage & Solubility Information
Storagekeep away from moisture,keep away from direct sunlight,store at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: < 0.1 mg/mL (insoluble)
DMF: 50 mg/mL (43.73 mM), Sonication is recommended.
Solution Preparation Table
DMF
1mg5mg10mg50mg
1 mM0.8747 mL4.3734 mL8.7468 mL43.7342 mL
5 mM0.1749 mL0.8747 mL1.7494 mL8.7468 mL
10 mM0.0875 mL0.4373 mL0.8747 mL4.3734 mL
20 mM0.0437 mL0.2187 mL0.4373 mL2.1867 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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