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Sincalide (Alias: SQ19844, Cholecystokinin octapeptide, CCK-8)

Name: Sincalide
Brand: TargetMol
SKU: TP1197
Price: 213 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. TP1197 Copy Product Info

Purity: 98.32%

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Sincalide (CCK-8) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin.

Sincalide

Copy Product Info

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Catalog No. TP1197

Alias SQ19844, Cholecystokinin octapeptide, CCK-8

Sincalide (CCK-8) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin.

Cas No. 25126-32-3

Pack Size	Price	USA Stock	Global Stock
1 mg	$213	In Stock	In Stock
5 mg	$593	In Stock	In Stock
10 mg	$950	In Stock	In Stock
25 mg	$1,660	In Stock	In Stock
50 mg	$2,660	In Stock	-

In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:98.32%

Color:White

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COA HPLC MS

Product Introduction

Bioactivity

Description	Sincalide (CCK-8) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin.
Synonyms	SQ19844, Cholecystokinin octapeptide, CCK-8

Chemical Properties

Molecular Weight	1143.27
Formula	C₄₉H₆₂N₁₀O₁₆S₃
Cas No.	25126-32-3
Smiles	C([C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N)=O)=O)CC(O)=O)=O)CCSC)=O)NC(CNC([C@@H](NC([C@H](CC2=CC=C(OS(=O)(=O)O)C=C2)NC([C@H](CC(O)=O)N)=O)=O)CCSC)=O)=O)C=3C=4C(NC3)=CC=CC4
Relative Density.	1.440 g/cm3 (Predicted)
Sequence	Asp-{SO3H-Tyr}-Met-Gly-Trp-Met-Asp-Phe-NH2
Sequence Short	D-{SO3H-Tyr}-MGWMDF

Storage & Solubility Information

Storage

keep away from moisture,keep away from direct sunlight,store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: < 0.1 mg/mL (insoluble)

DMF: 50 mg/mL (43.73 mM), Sonication is recommended.

Solution Preparation Table

DMF

	1mg	5mg	10mg	50mg
1 mM	0.8747 mL	4.3734 mL	8.7468 mL	43.7342 mL
5 mM	0.1749 mL	0.8747 mL	1.7494 mL	8.7468 mL
10 mM	0.0875 mL	0.4373 mL	0.8747 mL	4.3734 mL
20 mM	0.0437 mL	0.2187 mL	0.4373 mL	2.1867 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc