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Sincalide

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Catalog No. TP1197Cas No. 25126-32-3
Alias SQ19844, Cholecystokinin octapeptide, CCK-8

Sincalide (CCK-8) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin.

Sincalide
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Sincalide

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Purity: 98.32%
Catalog No. TP1197Alias SQ19844, Cholecystokinin octapeptide, CCK-8Cas No. 25126-32-3
Sincalide (CCK-8) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$89In StockIn Stock
2 mg$133In StockIn Stock
5 mg$247In StockIn Stock
10 mg$397In StockIn Stock
25 mg$652In StockIn Stock
50 mg$913In StockIn Stock
100 mg$1,230BackorderBackorder
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.32%
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COA HPLC MS

Product Introduction

Bioactivity
Description
Sincalide (CCK-8) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin.
SynonymsSQ19844, Cholecystokinin octapeptide, CCK-8
Chemical Properties
Molecular Weight1143.27
FormulaC49H62N10O16S3
Cas No.25126-32-3
SmilesC([C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N)=O)=O)CC(O)=O)=O)CCSC)=O)NC(CNC([C@@H](NC([C@H](CC2=CC=C(OS(=O)(=O)O)C=C2)NC([C@H](CC(O)=O)N)=O)=O)CCSC)=O)=O)C=3C=4C(NC3)=CC=CC4
Relative Density.1.440 g/cm3 (Predicted)
ColorWhite
AppearanceViscous
SequenceAsp-{SO3H-Tyr}-Met-Gly-Trp-Met-Asp-Phe-NH2
Sequence ShortD-{SO3H-Tyr}-MGWMDF-NH2
Storage & Solubility Information
Storagekeep away from moisture | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: < 0.1 mg/mL (insoluble)
DMF: 50 mg/mL (43.73 mM), Sonication is recommended.
Solution Preparation Table
DMF
1mg5mg10mg50mg
1 mM0.8747 mL4.3734 mL8.7468 mL43.7342 mL
5 mM0.1749 mL0.8747 mL1.7494 mL8.7468 mL
10 mM0.0875 mL0.4373 mL0.8747 mL4.3734 mL
20 mM0.0437 mL0.2187 mL0.4373 mL2.1867 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

SQ-19844SQ 19844SincalideProtein kinase Bpostevacuation cholecystographyPKBPI3K/AktPI3KPhosphoinositide 3-kinaseInhibitorinhibitinflammationCK‐8Cholecystokinin ReceptorCCK8CCK ReceptorCCK 8CCKcardiovascular hormoneApoptosisAkt
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