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IBT6A

Name: IBT6A
Brand: TargetMol
SKU: T10625
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T10625Cas No. 1022150-12-4

IBT6A, an impurity of Ibrutinib, is a Btk inhibitor (IC50: 0.5 nM) that can be utilized in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.

IBT6A

🥰Excellent

Purity: 99.88%

Catalog No. T10625Cas No. 1022150-12-4

IBT6A, an impurity of Ibrutinib, is a Btk inhibitor (IC50: 0.5 nM) that can be utilized in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.

Pack Size	Price	Availability	Quantity
100 mg	$42	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock

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Batch Information

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Purity:99.88%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description

IBT6A, an impurity of Ibrutinib, is a Btk inhibitor (IC50: 0.5 nM) that can be utilized in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.

Chemical Properties

Molecular Weight	386.45
Formula	C₂₂H₂₂N₆O
Cas No.	1022150-12-4
Smiles	NC1=C2C(=NN(C2=NC=N1)[C@@H]3CCCNC3)C4=CC=C(OC5=CC=CC=C5)C=C4
Relative Density.	1.39 g/cm3 (Predicted)
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25 mg/mL (64.69 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5877 mL	12.9383 mL	25.8766 mL	129.3828 mL
5 mM	0.5175 mL	2.5877 mL	5.1753 mL	25.8766 mL
10 mM	0.2588 mL	1.2938 mL	2.5877 mL	12.9383 mL
20 mM	0.1294 mL	0.6469 mL	1.2938 mL	6.4691 mL
50 mM	0.0518 mL	0.2588 mL	0.5175 mL	2.5877 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc