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BAMB-4

🥰Excellent
Catalog No. T14496Cas No. 891025-25-5
Alias ITPKA-IN-C14

BAMB-4 (ITPKA-IN-C14) is a highly membrane-permeable inhibitor of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA), effectively suppressing the metastasis-promoting effect of ITPKA in lung tumor cells (with IC50 of 37 μM in ADP-Glo Assay).

BAMB-4

BAMB-4

🥰Excellent
Purity: 98.57%
Catalog No. T14496Alias ITPKA-IN-C14Cas No. 891025-25-5
BAMB-4 (ITPKA-IN-C14) is a highly membrane-permeable inhibitor of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA), effectively suppressing the metastasis-promoting effect of ITPKA in lung tumor cells (with IC50 of 37 μM in ADP-Glo Assay).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$53In StockIn Stock
2 mg$75In StockIn Stock
5 mg$119In StockIn Stock
10 mg$178In StockIn Stock
25 mg$335In StockIn Stock
50 mg$469In StockIn Stock
100 mg$653In StockIn Stock
200 mg$879-In Stock
1 mL x 10 mM (in DMSO)$125In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.57%
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Product Introduction

Bioactivity
Description
BAMB-4 (ITPKA-IN-C14) is a highly membrane-permeable inhibitor of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA), effectively suppressing the metastasis-promoting effect of ITPKA in lung tumor cells (with IC50 of 37 μM in ADP-Glo Assay).
SynonymsITPKA-IN-C14
Chemical Properties
Molecular Weight252.27
FormulaC15H12N2O2
Cas No.891025-25-5
SmilesCc1ccc(cc1)C(=O)Nc1noc2ccccc12
Relative Density.1.295 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 39 mg/mL (154.6 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+90% Corn Oil: 2 mg/mL (7.93 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.9640 mL19.8200 mL39.6401 mL198.2003 mL
5 mM0.7928 mL3.9640 mL7.9280 mL39.6401 mL
10 mM0.3964 mL1.9820 mL3.9640 mL19.8200 mL
20 mM0.1982 mL0.9910 mL1.9820 mL9.9100 mL
50 mM0.0793 mL0.3964 mL0.7928 mL3.9640 mL
100 mM0.0396 mL0.1982 mL0.3964 mL1.9820 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Phosphatasemixed inhibition typelung cancerkinaseITPKAInhibitorinhibitcellular uptakeBAMB-4BAMB4BAMB 4
Related Tags: buy BAMB-4 | purchase BAMB-4 | BAMB-4 cost | order BAMB-4 | BAMB-4 chemical structure | BAMB-4 formula | BAMB-4 molecular weight
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