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L-Norleucine

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Catalog No. T4765Cas No. 327-57-1
Alias alpha-Aminocaproic acid, (S)-Norleucine, (S)-2-Aminohexanoic acid

L-Norleucine ((S)-Norleucine) is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.

L-Norleucine
Other Forms of L-Norleucine:
2-Aminohexanoic acidT66086616-06-8
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L-Norleucine

😃Good
Purity: 98.35%
Catalog No. T4765Alias alpha-Aminocaproic acid, (S)-Norleucine, (S)-2-Aminohexanoic acidCas No. 327-57-1
L-Norleucine ((S)-Norleucine) is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.
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Purity:98.35%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
L-Norleucine ((S)-Norleucine) is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.
In vitro
L-Norleucine interacts with hnRNPA2/B1 protein to suppresses the expressions of Twist1 and Snail, two inhibitors of E-cadherin, and promotes the expression of E-cadherin, resulting in the inhibition of tumor metastasis.
Synonymsalpha-Aminocaproic acid, (S)-Norleucine, (S)-2-Aminohexanoic acid
Chemical Properties
Molecular Weight131.17
FormulaC6H13NO2
Cas No.327-57-1
Smiles[C@@H](C(O)=O)(CCCC)N
Relative Density.1.1720 g/cm3 (Estimated)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: Soluble
DMSO: Slightly soluble

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

α-Aminocaproic acidNorleucineL-NorleucineLNorleucineL NorleucineInhibitorinhibitInfluenzaVirusInfluenza VirusEndogenousMetaboliteEndogenous Metabolitea-Aminocaproic acid2-Aminohexanoic acid
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