Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BRD7-IN-2 (compound 2-77) is a potent selective inhibitor of bromodomain-containing protein 7 (BRD7), exhibiting significant anti-proliferative activity in prostate cancer cells. It demonstrates an IC50 of 5.4 μM for BRD7 while showing weak inhibition for BRD9 with an IC50 of <300 μM.
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Description | BRD7-IN-2 (compound 2-77) is a potent selective inhibitor of bromodomain-containing protein 7 (BRD7), exhibiting significant anti-proliferative activity in prostate cancer cells. It demonstrates an IC50 of 5.4 μM for BRD7 while showing weak inhibition for BRD9 with an IC50 of >300 μM. |
In vitro | BRD7-IN-2 (compound 2-77) exhibits inhibitory activity against BRD7 and BRD9 in HEK293T cells, with IC50 values of 1.1 μM and 3.2 μM, respectively [1]. |
Molecular Weight | 310.35 |
Formula | C18H18N2O3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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BRD7-IN-2 Chromatin/Epigenetic Epigenetic Reader Domain inhibitor inhibit