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Fomesafen

Name: Fomesafen
Brand: TargetMol
SKU: T20622
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T20622Cas No. 72178-02-0

Alias PP-021, PP021, PP 021

Fomesafen (PP-021) is a diphenyl ether herbicide and an inhibitor of efficient and selective protoporphyrinogen IX oxidase (PPO).

Fomesafen

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Purity: 99.93%

Catalog No. T20622Alias PP-021, PP021, PP 021Cas No. 72178-02-0

Fomesafen (PP-021) is a diphenyl ether herbicide and an inhibitor of efficient and selective protoporphyrinogen IX oxidase (PPO).

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$30	In Stock	In Stock
50 mg	$50	In Stock	In Stock
100 mg	$83	In Stock	In Stock
200 mg	$118	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$31	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.93%

Appearance:Solid

Color:White

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COA LCMS HNMR

Product Introduction

Fomesafen AI Summary

Fomesafen exhibits multiple bioactivities including acting as an antagonist of the peroxisome proliferator-activated receptor gamma signaling pathway with a potency of 44,668.4 nM and as an agonist of the antioxidant response element (ARE) signaling pathway with a potency of 21,689.9 nM. It also demonstrates notable phytotoxicity against various plants. In Phaseolus vulgaris (dry beans), it shows crop injury with activity levels of 5.0% and 1.0-1.4% depending on the bean variety, and impacts plant growth parameters such as crop yield, shoot dry weight, and plant height, especially at higher doses. Furthermore, it affects Vigna angularis (adzuki bean) by reducing crop yield and seed moisture content, decreasing shoot dry weight by 16.0%, and causing visible injury at various dosages. Additionally, Fomesafen exhibits herbicidal activity against weeds like Veronica persica, Abutilon theophrasti, and Galium spurium var. echinospermon with high levels of efficacy, but shows lower effectiveness against Avena fatua, Glycine max, and Triticum aestivum..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Fomesafen (PP-021) is a diphenyl ether herbicide and an inhibitor of efficient and selective protoporphyrinogen IX oxidase (PPO).
Synonyms	PP-021, PP021, PP 021

Chemical Properties

Molecular Weight	438.76
Formula	C₁₅H₁₀ClF₃N₂O₆S
Cas No.	72178-02-0
Smiles	C(NS(C)(=O)=O)(=O)C1=C(N(=O)=O)C=CC(OC2=C(Cl)C=C(C(F)(F)F)C=C2)=C1
Relative Density.	1.574 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (113.96 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.56 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2792 mL	11.3958 mL	22.7915 mL	113.9575 mL
5 mM	0.4558 mL	2.2792 mL	4.5583 mL	22.7915 mL
10 mM	0.2279 mL	1.1396 mL	2.2792 mL	11.3958 mL
20 mM	0.1140 mL	0.5698 mL	1.1396 mL	5.6979 mL
50 mM	0.0456 mL	0.2279 mL	0.4558 mL	2.2792 mL
100 mM	0.0228 mL	0.1140 mL	0.2279 mL	1.1396 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc