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Mk-6186 HCl

Name: Mk-6186 HCl
Brand: TargetMol
SKU: T68103L
Price: 82 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T68103L

Alias Mk-6186 HCl(1034474-19-5 Free base)

MK-6186 HCl, a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity, can be used to study HIV.

Mk-6186 HCl

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Purity: 97.04%

Catalog No. T68103LAlias Mk-6186 HCl(1034474-19-5 Free base)

MK-6186 HCl, a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity, can be used to study HIV.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$82	-	In Stock
5 mg	$195	-	In Stock
10 mg	$285	-	In Stock
25 mg	$449	-	In Stock
50 mg	$659	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:97.04%

Appearance:Solid

Color:Yellow

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	MK-6186 HCl, a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity, can be used to study HIV.
Synonyms	Mk-6186 HCl(1034474-19-5 Free base)

Chemical Properties

Molecular Weight	471.73
Formula	C₂₁H₁₃Cl₃N₆O
Smiles	N#CC1=CC(Cl)=CC(OC2=C(C=CC3=C2C=NN3CC4=NNC5=C4C=CC=N5)Cl)=C1.Cl
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (116.59 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1199 mL	10.5993 mL	21.1986 mL	105.9928 mL
5 mM	0.4240 mL	2.1199 mL	4.2397 mL	21.1986 mL
10 mM	0.2120 mL	1.0599 mL	2.1199 mL	10.5993 mL
20 mM	0.1060 mL	0.5300 mL	1.0599 mL	5.2996 mL
50 mM	0.0424 mL	0.2120 mL	0.4240 mL	2.1199 mL
100 mM	0.0212 mL	0.1060 mL	0.2120 mL	1.0599 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc