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Cyfluthrin

Name: Cyfluthrin
Brand: TargetMol
SKU: T37688
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T37688Cas No. 68359-37-5

Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests.

Cyfluthrin

🥰Excellent

Purity: 99.76%

Catalog No. T37688Cas No. 68359-37-5

Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests.

Pack Size	Price	Availability
100 mg	$30	In Stock
500 mg	$59	In Stock
1 g	$83	In Stock
2 g	$123	In Stock
1 mL x 10 mM (in DMSO)	$31	In Stock

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Purity:99.76%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests.
Targets&IC50	ROS:19.39 μM
In vitro	Cell viability MTT assay was carried out to assess cyfluthrin cytotoxicity; IC30 and IC50 values for cyfluthrin were calculated to be 4.81 ± 0.92 μM and 19.39 ± 3.44 μM, respectively. Cyfluthrin increased significantly gene expressions of apoptosis, proinflammation and oxidative stress (Bax, Bcl-2, Casp-3, BNIP3, AKT1, p53, APAF1, NFκB1, TNFα and Nrf2) mediators. In the most genes, the mRNA levels induced by cyfluthrin were partially reduced by MEL (1 μM)[1].

Chemical Properties

Molecular Weight	434.29
Formula	C₂₂H₁₈Cl₂FNO₃
Cas No.	68359-37-5
Smiles	C(OC(C#N)C1=CC(OC2=CC=CC=C2)=C(F)C=C1)(=O)C3C(C=C(Cl)Cl)C3(C)C
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Chloroform: Slightly soluble

DMSO: 55 mg/mL (126.64 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3026 mL	11.5130 mL	23.0261 mL	115.1304 mL
5 mM	0.4605 mL	2.3026 mL	4.6052 mL	23.0261 mL
10 mM	0.2303 mL	1.1513 mL	2.3026 mL	11.5130 mL
20 mM	0.1151 mL	0.5757 mL	1.1513 mL	5.7565 mL
50 mM	0.0461 mL	0.2303 mL	0.4605 mL	2.3026 mL
100 mM	0.0230 mL	0.1151 mL	0.2303 mL	1.1513 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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