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Aurothiomalate sodium

🥰Excellent
Catalog No. T20168Cas No. 74916-57-7
Alias Sodium aurothiomalate, Myocrisine, Myocrisin, Myochrysine, Miochrysin, gold sodium thiomalate

Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-ι signaling. Aurothiomalate sodium is a potent thioredoxin reductase (TrxR) inhibitor. Aurothiomalate sodium exhibits potent anti-tumor activity.

Aurothiomalate sodium

Aurothiomalate sodium

🥰Excellent
Purity: 99.66%
Catalog No. T20168Alias Sodium aurothiomalate, Myocrisine, Myocrisin, Myochrysine, Miochrysin, gold sodium thiomalateCas No. 74916-57-7
Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-ι signaling. Aurothiomalate sodium is a potent thioredoxin reductase (TrxR) inhibitor. Aurothiomalate sodium exhibits potent anti-tumor activity.
Pack SizePriceAvailabilityQuantity
5 mg$47In Stock
10 mg$72In Stock
25 mg$147In Stock
50 mg$228In Stock
100 mg$372In Stock
200 mg$549In Stock
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Purity:99.66%
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Product Introduction

Bioactivity
Description
Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-ι signaling. Aurothiomalate sodium is a potent thioredoxin reductase (TrxR) inhibitor. Aurothiomalate sodium exhibits potent anti-tumor activity.
SynonymsSodium aurothiomalate, Myocrisine, Myocrisin, Myochrysine, Miochrysin, gold sodium thiomalate
Chemical Properties
Molecular Weight390.07
FormulaC4H3AuNa2O4S
Cas No.74916-57-7
SmilesO=C(CC(C([O-])=O)[S-])[O-].[Na+].[Au+].[Na+]
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 200 mg/mL (512.73 mM), Sonication is recommended.
DMSO: Insoluble
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM2.5636 mL12.8182 mL25.6364 mL128.1821 mL
5 mM0.5127 mL2.5636 mL5.1273 mL25.6364 mL
10 mM0.2564 mL1.2818 mL2.5636 mL12.8182 mL
20 mM0.1282 mL0.6409 mL1.2818 mL6.4091 mL
50 mM0.0513 mL0.2564 mL0.5127 mL2.5636 mL
100 mM0.0256 mL0.1282 mL0.2564 mL1.2818 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

TrxRTNFathioredoxinSCLCreductaseProtein kinase CPKC-ιPKCNSCLCNF-kBMekLACsLACInhibitorinhibitH510H460H2170H187H1703H1437ErkAurothiomalate sodiumAurothiomalateanti-rheumatoidA549A427
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