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Aurothiomalate sodium

Name: Aurothiomalate sodium
Brand: TargetMol
SKU: T20168
Price: 47 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T20168Cas No. 74916-57-7

Alias Sodium aurothiomalate, Myocrisine, Myocrisin, Myochrysine, Miochrysin, gold sodium thiomalate

Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-ι signaling. Aurothiomalate sodium is a potent thioredoxin reductase (TrxR) inhibitor. Aurothiomalate sodium exhibits potent anti-tumor activity.

Aurothiomalate sodium

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Purity: 99.66%

Catalog No. T20168Alias Sodium aurothiomalate, Myocrisine, Myocrisin, Myochrysine, Miochrysin, gold sodium thiomalateCas No. 74916-57-7

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$47	In Stock	In Stock
10 mg	$72	In Stock	In Stock
25 mg	$147	In Stock	In Stock
50 mg	$228	In Stock	In Stock
100 mg	$372	In Stock	In Stock
200 mg	$549	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.66%

Appearance:Solid

Color:White

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-ι signaling. Aurothiomalate sodium is a potent thioredoxin reductase (TrxR) inhibitor. Aurothiomalate sodium exhibits potent anti-tumor activity.
Synonyms	Sodium aurothiomalate, Myocrisine, Myocrisin, Myochrysine, Miochrysin, gold sodium thiomalate

Chemical Properties

Molecular Weight	390.07
Formula	C₄H₃AuNa₂O₄S
Cas No.	74916-57-7
Smiles	O=C(CC(C([O-])=O)[S-])[O-].[Na+].[Au+].[Na+]
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 200 mg/mL (512.73 mM), Sonication is recommended.

DMSO: Insoluble

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	2.5636 mL	12.8182 mL	25.6364 mL	128.1821 mL
5 mM	0.5127 mL	2.5636 mL	5.1273 mL	25.6364 mL
10 mM	0.2564 mL	1.2818 mL	2.5636 mL	12.8182 mL
20 mM	0.1282 mL	0.6409 mL	1.2818 mL	6.4091 mL
50 mM	0.0513 mL	0.2564 mL	0.5127 mL	2.5636 mL
100 mM	0.0256 mL	0.1282 mL	0.2564 mL	1.2818 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc