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Tizanidine hydrochloride

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Catalog No. T0290Cas No. 64461-82-1
Alias Tizanidine HCl, DS 103-282

Tizanidine hydrochloride (Tizanidine HCl), an α2-adrenergic receptor agonist, inhibits neurotransmitter release from CNS noradrenergic neurons.

Tizanidine hydrochloride
Other Forms of Tizanidine hydrochloride:
TizanidineT706551322-75-9
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Tizanidine hydrochloride

🥰Excellent
Purity: 99.96%
Catalog No. T0290Alias Tizanidine HCl, DS 103-282Cas No. 64461-82-1
Tizanidine hydrochloride (Tizanidine HCl), an α2-adrenergic receptor agonist, inhibits neurotransmitter release from CNS noradrenergic neurons.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$47In StockIn Stock
25 mg$58In StockIn Stock
50 mg$87In StockIn Stock
100 mg$107In StockIn Stock
200 mg$135In StockIn Stock
500 mg$223In StockIn Stock
1 mL x 10 mM (in DMSO)$32In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.96%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
Tizanidine hydrochloride (Tizanidine HCl), an α2-adrenergic receptor agonist, inhibits neurotransmitter release from CNS noradrenergic neurons.
SynonymsTizanidine HCl, DS 103-282
Chemical Properties
Molecular Weight290.17
FormulaC9H9Cl2N5S
Cas No.64461-82-1
SmilesCl.Clc1c(NC2=NCCN2)c2nsnc2cc1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (155.08 mM), Sonication is recommended.
H2O: 29 mg/mL (99.94 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (17.23 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM3.4463 mL17.2313 mL34.4626 mL172.3128 mL
5 mM0.6893 mL3.4463 mL6.8925 mL34.4626 mL
10 mM0.3446 mL1.7231 mL3.4463 mL17.2313 mL
20 mM0.1723 mL0.8616 mL1.7231 mL8.6156 mL
50 mM0.0689 mL0.3446 mL0.6893 mL3.4463 mL
DMSO
1mg5mg10mg50mg
100 mM0.0345 mL0.1723 mL0.3446 mL1.7231 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

α2 adrenergic receptorTizanidine hydrochlorideTizanidine HydrochlorideTizanidineInhibitorinhibitBeta ReceptorAdrenergicReceptorAdrenergic Receptor
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