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LY2928057
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Catalog No. T77383
Alias LY 2928057
LY2928057 is a humanized monoclonal antibody targeting the iron transporter SLC40A1, an iron-regulatory inhibitor used in cardiovascular disease research.
LY2928057
LY2928057
😃Good
Catalog No. T77383Alias LY 2928057
LY2928057 is a humanized monoclonal antibody targeting the iron transporter SLC40A1, an iron-regulatory inhibitor used in cardiovascular disease research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $372 | - | In Stock | |
| 5 mg | $1,180 | - | In Stock | |
| 10 mg | $1,880 | - | In Stock | |
| 25 mg | $2,830 | - | In Stock | |
| 50 mg | $3,820 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:>95.0% (SDS-PAGE); 99.49% (SEC-HPLC)
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| Description | LY2928057 is a humanized monoclonal antibody targeting the iron transporter SLC40A1, an iron-regulatory inhibitor used in cardiovascular disease research. |
| In vitro | LY2928057 is a monoclonal antibody targeting iron transporters. LY2928057 binds to ferritransporter and blocks its interaction with ferrimodulin, resulting in iron efflux, resulting in elevated serum iron and transferrin saturation levels and increased ferrimodulin in monkeys and humans. [1] |
| In vivo | The administration of LY2928057 (10-30 mg/kg) resulted in a dose-dependent increase in serum ferritin in cynomophores.[2] |
| Synonyms | LY 2928057 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | SLC40A1 |
| Molecular Weight | 114.02 kDa |
| Smiles | #N/A |
| Isotype | Human IgG4SP kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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