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LY2928057 (Synonyms: LY 2928057)

Catalog No. T77383 Copy Product Info
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LY2928057 is a humanized monoclonal antibody targeting the iron transporter SLC40A1, an iron-regulatory inhibitor used in cardiovascular disease research.

LY2928057

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Catalog No. T77383
Synonyms LY 2928057

LY2928057 is a humanized monoclonal antibody targeting the iron transporter SLC40A1, an iron-regulatory inhibitor used in cardiovascular disease research.

LY2928057
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$372-In Stock
5 mg$1,180-In Stock
10 mg$1,880-In Stock
25 mg$2,830-In Stock
50 mg$3,820-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:>95.0% (SDS-PAGE); 99.49% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
LY2928057 is a humanized monoclonal antibody targeting the iron transporter SLC40A1, an iron-regulatory inhibitor used in cardiovascular disease research.
In vitro
LY2928057 is a monoclonal antibody targeting iron transporters. LY2928057 binds to ferritransporter and blocks its interaction with ferrimodulin, resulting in iron efflux, resulting in elevated serum iron and transferrin saturation levels and increased ferrimodulin in monkeys and humans. [1]
In vivo
The administration of LY2928057 (10-30 mg/kg) resulted in a dose-dependent increase in serum ferritin in cynomophores.[2]
SynonymsLY 2928057
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetSLC40A1
Chemical Properties
Molecular Weight114.02 kDa
Smiles#N/A
Antibody Information
IsotypeHuman IgG4SP kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature | Shipping with blue ice/Shipping at ambient temperature.

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