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Imidazoleacetic acid hydrochloride

🥰Excellent
Catalog No. T4753Cas No. 3251-69-2
Alias I4AA, 4-Imidazoleacetic acid hydrochloride, (4-Imidazolyl)acetic acid hydrochloride

Imidazoleacetic acid hydrochloride (I4AA) is an imidazole derivative with potential antituberculosis properties. It also used in the preparation of acyl guanidine inhibitors of β-secretase.

Imidazoleacetic acid hydrochloride

Imidazoleacetic acid hydrochloride

🥰Excellent
Purity: 99.50%
Catalog No. T4753Alias I4AA, 4-Imidazoleacetic acid hydrochloride, (4-Imidazolyl)acetic acid hydrochlorideCas No. 3251-69-2
Imidazoleacetic acid hydrochloride (I4AA) is an imidazole derivative with potential antituberculosis properties. It also used in the preparation of acyl guanidine inhibitors of β-secretase.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 g$35-In Stock
1 mL x 10 mM (in DMSO)$30In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.50%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Imidazoleacetic acid hydrochloride (I4AA) is an imidazole derivative with potential antituberculosis properties. It also used in the preparation of acyl guanidine inhibitors of β-secretase.
SynonymsI4AA, 4-Imidazoleacetic acid hydrochloride, (4-Imidazolyl)acetic acid hydrochloride
Chemical Properties
Molecular Weight162.57
FormulaC5H7ClN2O2
Cas No.3251-69-2
SmilesCl.OC(=O)Cc1cnc[nH]1
Relative Density.1.426g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (338.32 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (12.3 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM6.1512 mL30.7560 mL61.5120 mL307.5598 mL
5 mM1.2302 mL6.1512 mL12.3024 mL61.5120 mL
10 mM0.6151 mL3.0756 mL6.1512 mL30.7560 mL
20 mM0.3076 mL1.5378 mL3.0756 mL15.3780 mL
50 mM0.1230 mL0.6151 mL1.2302 mL6.1512 mL
100 mM0.0615 mL0.3076 mL0.6151 mL3.0756 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

tuberculosisInhibitorinhibitImidazoleacetic acid hydrochlorideImidazoleacetic acid HydrochlorideImidazoleacetic acidEndogenousMetaboliteEndogenous Metabolite4-Imidazoleacetic acid Hydrochloride(4-Imidazolyl)acetic acid Hydrochloride
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