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Transcrocetinate disodium

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Catalog No. TQ0027Cas No. 591230-99-8
Alias Disodium trans-crocetinate

Transcrocetinate disodium (Disodium trans-crocetinate), extracted from saffron (Crocus sativus L.), is a high-affinity antagonist of NMDA receptor.

Transcrocetinate disodium

Transcrocetinate disodium

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Purity: 99.22%
Catalog No. TQ0027Alias Disodium trans-crocetinateCas No. 591230-99-8
Transcrocetinate disodium (Disodium trans-crocetinate), extracted from saffron (Crocus sativus L.), is a high-affinity antagonist of NMDA receptor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$38In StockIn Stock
5 mg$89In StockIn Stock
10 mg$122In StockIn Stock
25 mg$218In StockIn Stock
50 mg$319In StockIn Stock
100 mg$477In StockIn Stock
1 mL x 10 mM (in DMSO)$105In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.22%
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Product Introduction

Bioactivity
Description
Transcrocetinate disodium (Disodium trans-crocetinate), extracted from saffron (Crocus sativus L.), is a high-affinity antagonist of NMDA receptor.
In vitro
Transcrocetinate has been shown to exert strong NMDA receptor affinity and is thought to be responsible for the CNS activity of saffron. Transcrocetinate at 10 μM level does not change viability while higher concentrations (40-160 μM) reduces significantly cellular viability.
SynonymsDisodium trans-crocetinate
Chemical Properties
Molecular Weight372.37
FormulaC20H22Na2O4
Cas No.591230-99-8
SmilesO=C([O-])/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C([O-])=O.[Na+].[Na+]
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 4.42 mg/mL (11.87 mM), Sonication is recommended.
DMSO: Insoluble
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM2.6855 mL13.4275 mL26.8550 mL134.2750 mL
5 mM0.5371 mL2.6855 mL5.3710 mL26.8550 mL
10 mM0.2686 mL1.3428 mL2.6855 mL13.4275 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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