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SD49-7

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Catalog No. T67781Cas No. 54009-54-0
Alias HNASH

SD49-7 is an inhibitor of histone lysine demethylase 4 (KDM4) with an IC50 of 0.19 µM.

SD49-7

SD49-7

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Purity: 99.91%
Catalog No. T67781Alias HNASHCas No. 54009-54-0
SD49-7 is an inhibitor of histone lysine demethylase 4 (KDM4) with an IC50 of 0.19 µM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$55In StockIn Stock
5 mg$133In StockIn Stock
10 mg$198In StockIn Stock
25 mg$398In StockIn Stock
50 mg$578In StockIn Stock
100 mg$827-In Stock
500 mg$1,650-In Stock
1 mL x 10 mM (in DMSO)$152In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.91%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
SD49-7 is an inhibitor of histone lysine demethylase 4 (KDM4) with an IC50 of 0.19 µM.
Targets&IC50
KDM4:0.19 μM
SynonymsHNASH
Chemical Properties
Molecular Weight306.32
FormulaC18H14N2O3
Cas No.54009-54-0
SmilesC(=NNC(=O)C1=C(O)C=CC=C1)C=2C3=C(C=CC2O)C=CC=C3
Relative Density.1.28 g/cm3 (Predicted)
ColorYellow
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 4.5 mg/mL (14.69 mM), Sonication is recommended.
DMSO: 54.9 mg/mL (179.22 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM3.2646 mL16.3228 mL32.6456 mL163.2280 mL
5 mM0.6529 mL3.2646 mL6.5291 mL32.6456 mL
10 mM0.3265 mL1.6323 mL3.2646 mL16.3228 mL
DMSO
1mg5mg10mg50mg
20 mM0.1632 mL0.8161 mL1.6323 mL8.1614 mL
50 mM0.0653 mL0.3265 mL0.6529 mL3.2646 mL
100 mM0.0326 mL0.1632 mL0.3265 mL1.6323 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

SD49-7KDM4HistoneDemethylaseHistone Demethylase
Related Tags: buy SD49-7 | purchase SD49-7 | SD49-7 cost | order SD49-7 | SD49-7 chemical structure | SD49-7 formula | SD49-7 molecular weight
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