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IKK2-IN-4

Name: IKK2-IN-4
Brand: TargetMol
SKU: T36524
Price: 79 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T36524Cas No. 354811-10-2

Alias IKK2 Inhibitor IV, 5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide

IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.

IKK2-IN-4

🥰Excellent

Catalog No. T36524Alias IKK2 Inhibitor IV, 5-Phenyl-2-ureidothiophene-3-carboxylic Acid AmideCas No. 354811-10-2

IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.

Pack Size	Price	Availability
500 μg	$79	In Stock
1 mg	$116	In Stock
5 mg	$291	In Stock
10 mg	$446	In Stock
25 mg	$691	In Stock
50 mg	$931	In Stock
100 mg	$1,250	In Stock
200 mg	$1,670	In Stock

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Batch Information

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Purity:>99.99%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.
Targets&IC50	IKK2:25 nM
Synonyms	IKK2 Inhibitor IV, 5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide

Chemical Properties

Molecular Weight	261.3
Formula	C₁₂H₁₁N₃O₂S
Cas No.	354811-10-2
Smiles	N(C(N)=O)C=1SC(=CC1C(N)=O)C2=CC=CC=C2

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 2 mg/mL (7.65 mM), Sonication is recommended.

DMSO: 30 mg/mL (114.81 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8270 mL	19.1351 mL	38.2702 mL	191.3509 mL
5 mM	0.7654 mL	3.8270 mL	7.6540 mL	38.2702 mL

DMSO

	1mg	5mg	10mg	50mg
10 mM	0.3827 mL	1.9135 mL	3.8270 mL	19.1351 mL
20 mM	0.1914 mL	0.9568 mL	1.9135 mL	9.5675 mL
50 mM	0.0765 mL	0.3827 mL	0.7654 mL	3.8270 mL
100 mM	0.0383 mL	0.1914 mL	0.3827 mL	1.9135 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc