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Bikinin

🥰Excellent
Catalog No. T1965Cas No. 188011-69-0
Alias Abrasin

Bikinin (Abrasin), a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR receptor.

Bikinin

Bikinin

🥰Excellent
Purity: 99.86%
Catalog No. T1965Alias AbrasinCas No. 188011-69-0
Bikinin (Abrasin), a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR receptor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$39In StockIn Stock
25 mg$70In StockIn Stock
50 mg$122In StockIn Stock
100 mg$197In StockIn Stock
200 mg$293In StockIn Stock
500 mg$497-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.86%
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Product Introduction

Bioactivity
Description
Bikinin (Abrasin), a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR receptor.
In vitro
Bikinin directly inhibited BIN2 in Arabidopsis GSK-3s and activated oleuropein steroid-dependent gene expression.Bikinin also inhibited RD26 expression and, in the case of RD26pro:GUS, NaCl (150 mM)-induced GUS activity.
In vivo
Bikinin directly inhibited BIN2 in Arabidopsis GSK-3s and activated oleuropein steroid-dependent gene expression.Bikinin also inhibited RD26 expression and, in the case of RD26pro:GUS, NaCl (150 mM)-induced GUS activity.
SynonymsAbrasin
Chemical Properties
Molecular Weight273.08
FormulaC9H9BrN2O3
Cas No.188011-69-0
SmilesOC(=O)CCC(=O)NC1=NC=C(Br)C=C1
Relative Density.1.711 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 45 mg/mL (164.79 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.32 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6619 mL18.3097 mL36.6193 mL183.0965 mL
5 mM0.7324 mL3.6619 mL7.3239 mL36.6193 mL
10 mM0.3662 mL1.8310 mL3.6619 mL18.3097 mL
20 mM0.1831 mL0.9155 mL1.8310 mL9.1548 mL
50 mM0.0732 mL0.3662 mL0.7324 mL3.6619 mL
100 mM0.0366 mL0.1831 mL0.3662 mL1.8310 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Shaggy-like kinaseInhibitorinhibitGSK-3GSK3Glycogen synthase kinase-3Glycogen synthase kinase 3Bikinin
Related Tags: buy Bikinin | purchase Bikinin | Bikinin cost | order Bikinin | Bikinin chemical structure | Bikinin in vivo | Bikinin in vitro | Bikinin formula | Bikinin molecular weight
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